ArticleEuropean eating disorders review : the journal of the Eating Disorders Association2017
Association Between Oxytocin Receptor Genotype, Maternal Care, and Eating Disorder Behaviours in a Community Sample of Women.
Article in European eating disorders review : the journal of the Eating Disorders Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Genetic polymorphisms and their association with neurobiological and psychological factors in anorexia nervosa: a systematic review.Frontiers in psychology · 2024Pooled it
- The Oxytocin System and Implications for Oxytocin Deficiency in Hypothalamic-Pituitary Disease.Endocrine reviews · 2025Review
- Article
- Relationship of Genetic Polymorphisms and Microbial Composition with Binge Eating Disorder: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- The neurohypophyseal hormone oxytocin and eating behaviors: a narrative review.Hormones (Athens, Greece) · 2024Review
- Oxytocin response to food intake in avoidant/restrictive food intake disorder.European journal of endocrinology · 2023Article
- Roles of the Oxytocin Receptor (OXTR) in Human Diseases.International journal of molecular sciences · 2023Review
- Risk factors for eating disorders: findings from a rapid review.Journal of eating disorders · 2023Review
- OXTR DNA methylation differentiates men on the obesity spectrum with and without binge eating disorder.Clinical epigenetics · 2022Article
- Context matters: Neighborhood disadvantage is associated with increased disordered eating and earlier activation of genetic influences in girls.Journal of abnormal psychology · 2021Article
- Review of eating disorders and oxytocin receptor polymorphisms.Journal of eating disorders · 2021Review
- Hypothalamic Neuropeptide Brain Protection: Focus on Oxytocin.Journal of clinical medicine · 2020Review
- Purging disorder: recent advances and future challenges.Current opinion in psychiatry · 2019Review
- Childhood adversity and parenting behavior: the role of oxytocin receptor gene polymorphisms.Journal of neural transmission (Vienna, Austria : 1996) · 2019Article
- Assessment of Knowledge, Attitudes, and Behaviors toward Eating Disorders among Adolescents in Italy.International journal of environmental research and public health · 2019Article
- Role of oxytocin in the control of stress and food intake.Journal of neuroendocrinology · 2019Review
- Brain-Derived Neurotrophic Factor and Oxytocin Signaling in Association With Clinical Symptoms in Adolescent Inpatients With Anorexia Nervosa-A Longitudinal Study.Frontiers in psychiatry · 2019Article
- The Neuropeptide Hormone Oxytocin in Eating Disorders.Current psychiatry reports · 2018Review
- Oxytocin Receptor Polymorphism Decreases Midline Neural Activations to Social Stimuli in Anorexia Nervosa.Frontiers in psychology · 2018Article
- Oxytocin and Eating Disorders: A Narrative Review on Emerging Findings and Perspectives.Current neuropharmacology · 2018Review
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
Abstract
This study aimed to investigate associations between oxytocin receptor gene (OXT-R) polymorphisms (rs53576 and rs2254298), their interaction with maternal care (GxE), and ED behaviours in a community sample. We studied 3698 women from the Avon Longitudinal Study of Parents and Children (ALSPAC) who participated in a two-phase prevalence study of lifetime ED and had genotype data. The GG rs53576 genotype was associated with binge eating and purging, and the rs2254298 AG/AA genotype with restrictive eating lifetime. In addition, the rs2254298 AG/AA genotype interacted with poor maternal care to increase the odds of binge eating and purging (odds ratio = 4.40 (95% confidence intervals: 1.11-17.4)). This study replicates previous findings of an association between OXT-R polymorphisms and ED, and it is the first to show an interaction between OXT-R genotype and poor maternal care. As such, these findings highlight the important role of oxytocin in understanding the pathophysiology of ED. © 2016 The Authors European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd.
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Registered trials
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