Evidence map›Paper›PMID 27862095›Full record

ArticleAmerican journal of industrial medicine2017

Cognitive control dysfunction in workers exposed to manganese-containing welding fume.

Amal Al-Lozi, Susan Searles Nielsen, Tamara Hershey, Angela Birke, Harvey Checkoway, Susan R Criswell, Brad A Racette

Open access · greenAbstract read
In one paragraph

Article in American journal of industrial medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
10.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Article
  6. Review
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  8. Article
  9. Article
  10. The reproducibility of urinary ions in manganese exposed workers.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2019
    Article
  11. [Neurotoxicology · 2018
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Amal Al-LoziDepartment of Neurology, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Susan Searles NielsenDepartment of Neurology, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Tamara HersheyDepartment of Neurology, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Angela BirkeDepartment of Neurology, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Harvey CheckowayDepartment of Family Medicine and Public Health, University of California, San Diego, California.
Susan R CriswellDepartment of Neurology, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Brad A RacetteDepartment of Neurology, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Washington University in St. Louis · USUniversity of California, San Diego · US

Funding

WILDLIFE BIOMARKER APPLICATIONS TO REMEDIATION DECISION MAKINGP42ES004696 · NIEHS · UNIVERSITY OF WASHINGTON · PI GALLAGHER, EVAN P · 1987 to 2021
$51.2M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Imaging Biomarkers of Neurotoxicity in WeldersR01ES021488 · NIEHS · WASHINGTON UNIVERSITY · PI Brad A Racette · 2013 to 2026
$5.3M
Epidemiology of Parkinsonism in WeldersR01ES013743 · NIEHS · WASHINGTON UNIVERSITY · PI RACETTE, BRAD A · 2007 to 2011
$2.6M
Epidemiology and Biomarkers of Parkinsonism in WeldersK24ES017765 · NIEHS · WASHINGTON UNIVERSITY · PI RACETTE, BRAD A · 2009 to 2018
$1.5M
RESTING STATE FUNCTIONAL CONNECTIVITY MRI IN MANGANESE EXPOSED WELDERSK23ES021444 · NIEHS · WASHINGTON UNIVERSITY · PI CRISWELL, SUSAN · 2012 to 2016
$809k
NCATS NIH HHS UL1 TR000448NIEHS NIH HHS K23 ES021444NIEHS NIH HHS K24 ES017765NIEHS NIH HHS P42 ES004696NIEHS NIH HHS R01 ES013743NIEHS NIH HHS R01 ES021488
6 · The paper itself

Abstract

backgroundChronic exposure to manganese (Mn) is a health concern in occupations such as welding because of well-established motor effects due to basal ganglia dysfunction. We hypothesized that cognitive control (the ability to monitor, manipulate, and regulate ongoing cognitive demands) would also be affected by chronic Mn exposure.

methodsWe examined the relationship between Mn exposure and cognitive control performance in 95 workers with varying intensity and duration (median 15.5 years) of exposure to welding fume. We performed linear regression to assess the association between exposure to Mn-containing welding fume and cognitive control tasks.

resultsOverall performance was inversely related to intensity of welding exposure (P = 0.009) and was driven by the Two-Back and Letter Number Sequencing tests that assess working memory (both P = 0.02).

conclusionsOccupational exposure to Mn-containing welding fume may be associated with poorer working memory performance, and workers may benefit from practices that reduce exposure intensity. Am. J. Ind. Med. 60:181-188, 2017. © 2016 Wiley Periodicals, Inc.

Indexed as

Memory, Short-TermWeldingAdultAgedAir Pollutants, OccupationalFemaleHumansInhalation ExposureMaleManganeseMiddle AgedMidwestern United StatesNeuropsychological TestsOccupational DiseasesOccupational ExposureYoung AdultAir Pollutants, OccupationalManganesecaudate nucleuscognitive controlmanganesewelding

Identifiers

PMID27862095
PMCPMC5501991
OpenAlexW2559363454

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.