Evidence map›Paper›PMID 27862020›Full record

ArticleMuscle & nerve2017

Impaired calcium signaling in muscle fibers from intercostal and foot skeletal muscle in a cigarette smoke-induced mouse model of COPD.

Patrick Robison, Thomas E Sussan, Hegang Chen, Shyam Biswal, Martin F Schneider, Erick O Hernández-Ochoa

Open access · greenAbstract read
In one paragraph

Article in Muscle & nerve, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Contribution of skeletal muscle-specific microRNA-133b to insulin resistance in heart failure.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Loss of S100A1 expression leads to CaPhysiological reports · 2018
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Patrick RobisonDepartment of Biochemistry and Molecular Biology, University of Maryland School of Medicine, 108 N. Greene Street, Baltimore, Maryland, 21201, USA.
Thomas E SussanDepartment of Environmental Health Sciences, Johns Hopkins University School of Public Health, Baltimore, Maryland, USA.
Hegang ChenDivision of Biostatistics and Bioinformatics, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Shyam BiswalDepartment of Environmental Health Sciences, Johns Hopkins University School of Public Health, Baltimore, Maryland, USA.
Martin F SchneiderDepartment of Biochemistry and Molecular Biology, University of Maryland School of Medicine, 108 N. Greene Street, Baltimore, Maryland, 21201, USA.
Erick O Hernández-OchoaDepartment of Biochemistry and Molecular Biology, University of Maryland School of Medicine, 108 N. Greene Street, Baltimore, Maryland, 21201, USA.
University of Maryland, Baltimore · USBloomberg (United States) · USJohns Hopkins Medicine · USUniversity of Pennsylvania · US

Funding

Interdisciplinary Training Program Muscle BiologyT32AR007592 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI Aikaterini Kontrogianni-Konstantopoulos · 1996 to 2026
$11.7M
Roles of voltage sensor, S100A1 and calmodulin in skeletal muscle Ca2+ signalingR37AR055099 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI SCHNEIDER, MARTIN F · 2012 to 2021
$3.5M
NIAMS NIH HHS R37 AR055099NIAMS NIH HHS T32 AR007592
6 · The paper itself

Abstract

introductionRespiratory and locomotor skeletal muscle dysfunction are common findings in chronic obstructive pulmonary disease (COPD); however, the mechanisms that cause muscle impairment in COPD are unclear. Because Ca

methodsIntercostal and flexor digitorum brevis muscles from control and cigarette smoke-exposed mice were investigated. We used single cell Ca

resultsWe found impaired Ca

conclusionsCa

Indexed as

Action PotentialsAir PollutantsAnimalsCalciumCalcium SignalingCalmodulinDisease Models, AnimalFootGene Expression RegulationLocomotionMaleMiceMice, Inbred C57BLMuscle ContractionMuscle Fibers, SkeletalPulmonary Disease, Chronic ObstructiveAir PollutantsCalciumCalmodulinRyanodine Receptor Calcium Release ChannelS100A1 proteinS100 ProteinsCa2+ transientscigarette smokeCOPDexcitation-contraction couplinglocomotor musclerespiratory muscle

Identifiers

PMID27862020
PMCPMC5426995
OpenAlexW2551557276

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.