Evidence map›Paper›PMID 27861921›Full record

ReviewThe Journal of physiology2017

Potassium channels in the heart: structure, function and regulation.

Eleonora Grandi, Michael C Sanguinetti, Daniel C Bartos, Donald M Bers, Ye Chen-Izu, Nipavan Chiamvimonvat, Henry M Colecraft, Brian P Delisle, Jordi Heijman, Manuel F Navedo and 4 more

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 110 citations in OpenAlex.

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  14. The First KToxins · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Ion channels of cold transduction and transmission.The Journal of general physiology · 2024
    Review
  20. Targeting the ICirculation research · 2024
    Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 4 countries.

Eleonora GrandiDepartment of Pharmacology, University of California, Davis, Davis, CA, 95616, USA.
Michael C SanguinettiDepartment of Internal Medicine, University of Utah, Nora Eccles Harrison Cardiovascular Research and Training Institute, Salt Lake City, UT, 84112, USA.
Daniel C BartosDepartment of Pharmacology, University of California, Davis, Davis, CA, 95616, USA.
Donald M BersDepartment of Pharmacology, University of California, Davis, Davis, CA, 95616, USA.
Ye Chen-IzuDepartment of Pharmacology, University of California, Davis, Davis, CA, 95616, USA.
Nipavan ChiamvimonvatDepartment of Internal Medicine, Division of Cardiology, University of California, Davis, CA, 95616, USA.
Henry M ColecraftDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY, 10032, USA.
Brian P DelisleDepartment of Physiology, University of Kentucky, Lexington, KY, 40536, USA.
Jordi HeijmanDepartment of Cardiology, Cardiovascular Research Institute Maastricht, Faculty of Health, Medicine, and Life Sciences, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0002-1418-108X
Manuel F NavedoDepartment of Pharmacology, University of California, Davis, Davis, CA, 95616, USA.
Sergei NoskovCentre for Molecular Simulation, Department of Biological Sciences, University of Calgary, Calgary, AB, T2N 1N4, Canada.
Catherine ProenzaDepartment of Physiology and Biophysics, University of Colorado - Anschutz Medical Campus, Denver, CO, 80045, USA.
Jamie I VandenbergVictor Chang Cardiac Research Institute, Darlinghurst, NSW, 2010, Australia.
Vladimir Yarov-YarovoyDepartment of Physiology and Membrane Biology, University of California, Davis, CA, 95616, USA.
University of California, Davis · USColumbia University · USMaastricht University · NLUniversity of Calgary · CAUniversity of Colorado Anschutz Medical Campus · USUniversity of Kentucky · USUniversity of Utah · USVictor Chang Cardiac Research Institute · AU

Funding

Functional Interactions of Cardiac Ion ChannelsR01HL085844 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN · 2007 to 2025
$7.3M
POSTGRADUATE TRAINING IN CARDIOVASCULAR RESEARCHT32HL007822 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI BUTTRICK, PETER N., LEINWAND, LESLIE ANNE · 1996 to 2023
$6.2M
Regulation of excitability in sinoatrial myocytesR01HL088427 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI PROENZA, CATHERINE · 2008 to 2024
$5.8M
Translational Study of Cardiac DysfunctionR01HL085727 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN, SIRISH, PADMINI · 2008 to 2022
$5.7M
Phospholemman and Na-Pump Function in Cardiac MyocytesR01HL081562 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERS, DONALD M · 2005 to 2018
$5.3M
Sex-specific arrhythmogenic mechanisms of atrial fibrillationR01HL131517 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Eleonora Grandi · 2016 to 2026
$5.0M
Coupling of Vascular Cav1.2 Channels In Health & DiseaseR01HL121059 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NAVEDO, MANUEL F · 2015 to 2024
$4.5M
IONIC CONTROL OF CARDIAC MUSCLE CONTRACTION: EC COUPLINGR01HL030077 · NHLBI · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI BERS, DONALD M · 1986 to 2018
$3.8M
Multi-scale Systems Model of Murine Heart FailureR01HL105242 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BERS, DONALD M, MCCULLOCH, ANDREW D. · 2012 to 2016
$3.5M
Calcium Sparklets-Induced Vascular Dysfunction During DiabetesR01HL098200 · NHLBI · UNIVERSITY OF WASHINGTON · PI NAVEDO, MANUEL F · 2010 to 2019
$3.5M
Decoding the enigma of cardiac amplificationR01HL137228 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHIAMVIMONVAT, NIPAVAN · 2017 to 2020
$2.2M
Novel Cell-in-Gel System for Mechanotransduction Study at the Single Cell LevelR01HL123526 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN-IZU, YE · 2015 to 2018
$1.8M
BLRD VA I01 BX000576CSRD VA I01 CX001490NHLBI NIH HHS R01 HL030077NHLBI NIH HHS R01 HL081562NHLBI NIH HHS R01 HL085727NHLBI NIH HHS R01 HL085844NHLBI NIH HHS R01 HL088427NHLBI NIH HHS R01 HL098200NHLBI NIH HHS R01 HL105242NHLBI NIH HHS R01 HL121059NHLBI NIH HHS R01 HL122421NHLBI NIH HHS R01 HL123526NHLBI NIH HHS R01 HL131517NHLBI NIH HHS R01 HL137228NHLBI NIH HHS R13 HL132515NHLBI NIH HHS T32 HL007822
6 · The paper itself

Abstract

This paper is the outcome of the fourth UC Davis Systems Approach to Understanding Cardiac Excitation-Contraction Coupling and Arrhythmias Symposium, a biannual event that aims to bring together leading experts in subfields of cardiovascular biomedicine to focus on topics of importance to the field. The theme of the 2016 symposium was 'K

Indexed as

AnimalsHeartHumansPotassium Channels, Voltage-GatedPotassium Channels, Voltage-Gatedgatingheterogeneityphosphorylationtrafficking

Identifiers

PMID27861921
PMCPMC5374109
OpenAlexW2552848819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.