Evidence map›Paper›PMID 27861798›Full record

ArticleFEBS letters2016

Characterizing polyubiquitinated forms of the neurodegenerative ubiquitin mutant UBB

Michal Chojnacki, Daoning Zhang, Monika Talarowska, Piotr Gałecki, Janusz Szemraj, David Fushman, Mark A Nakasone

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. USP2-Related Cellular Signaling and Consequent Pathophysiological Outcomes.International journal of molecular sciences · 2021
    Review
  3. The Dose-Dependent Pleiotropic Effects of the UBBFrontiers in molecular biosciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michal ChojnackiDepartment of Medical Biochemistry, Medical University of Łódź, Poland.
Daoning ZhangDepartment of Chemistry and Biochemistry, Center for Biomolecular Structure and Organization, University of Maryland, College Park, MD, USA.
Monika TalarowskaDepartment of Adult Psychiatry, Medical University of Łódź, Poland.
Piotr GałeckiDepartment of Adult Psychiatry, Medical University of Łódź, Poland.
Janusz SzemrajDepartment of Medical Biochemistry, Medical University of Łódź, Poland.
David FushmanDepartment of Chemistry and Biochemistry, Center for Biomolecular Structure and Organization, University of Maryland, College Park, MD, USA.
Mark A NakasoneDepartment of Chemistry and Biochemistry, Center for Biomolecular Structure and Organization, University of Maryland, College Park, MD, USA.

Funding

Solution structure and dynamics of polyubiquitin chainsR01GM065334 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI DAVID FUSHMAN · 2002 to 2026
$6.2M
NIGMS NIH HHS R01 GM065334
6 · The paper itself

Abstract

The ubiquitin mutant UBB

Indexed as

AgedAlzheimer DiseaseCase-Control StudiesCysteine EndopeptidasesDeubiquitinating EnzymesEndopeptidasesEndosomal Sorting Complexes Required for TransportFemaleFluoresceinsFluorescent DyesGene Expression RegulationHumansMaleMiddle AgedModels, MolecularNeuronsCysteine EndopeptidasesDeubiquitinating EnzymesEndopeptidasesEndosomal Sorting Complexes Required for Transportfluorescein 5-maleimideFluoresceinsFluorescent DyesOTUB1 protein, humanOTUD3 protein, humanPolyubiquitinProteasome Endopeptidase ComplexProtein IsoformsSTAMBP protein, humanUBB protein, humanUbiquitinUbiquitin-Specific ProteasesUbiquitin ThiolesteraseUSP2 protein, humanbiomolecular NMRdeubiquitinaseneurodegenerationpolyubiquitinUBB +1

Identifiers

PMID27861798
PMCPMC5182158

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.