ArticleEpilepsia2016
Correlation of FDG-PET hypometabolism and SEEG epileptogenicity mapping in patients with drug-resistant focal epilepsy.
Article in Epilepsia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Seizure outcomes and complications associated with stereoelectroencephalography versus subdural electrodes for invasive monitoring in epilepsy surgery: a meta-analysis.Frontiers in neurology · 2025Pooled it
- Multimodal Imaging in Epilepsy Surgery for Personalized Neurosurgical Planning.Journal of personalized medicine · 2025Review
- Voxel-based and surface-based cortical morphometric MRI applications for identifying the epileptogenic zone: A narrative review.Epilepsia open · 2025Review
- Lateralizing value of interictal epileptiform discharges and other parameters in hypothalamic hamartoma.Epilepsia · 2025Article
- TSPO-PET in pre-surgical evaluations: Correlation of neuroinflammation and SEEG epileptogenicity mapping in drug-resistant focal epilepsy.Epilepsia · 2025Article
- Hypometabolic patterns are related to post-surgical seizure outcomes in focal cortical dysplasia: A semi-quantitative study.Epilepsia open · 2024Article
- Article
- Altered metabolic-functional coupling in the epileptogenic network could predict surgical outcomes of mesial temporal lobe epilepsy.Frontiers in neuroscience · 2023Article
- Potential new roles for glycogen in epilepsy.Epilepsia · 2023Review
- Alterations in Cortical-Subcortical Metabolism in Temporal Lobe Epilepsy With Impaired Awareness Seizures.Frontiers in aging neuroscience · 2022Article
- Article
- Editorial for "Neuroimaging Phenotyping and Structural-Metabolic-Epileptogenic Correlations in the Temporal Neocortex of Focal Cortical Dysplasia IIIa".Journal of magnetic resonance imaging : JMRI · 2021Article
- Efficacy of delayedEuropean journal of nuclear medicine and molecular imaging · 2021Article
- Relationship between PET metabolism and SEEG epileptogenicity in focal lesional epilepsy.European journal of nuclear medicine and molecular imaging · 2020Article
- Aberrant Metabolic Patterns Networks in Insular Epilepsy.Frontiers in neurology · 2020Article
- Glucose Metabolism Characteristics of Extra-Hypothalamic Cortex in Patients With Hypothalamic Hamartomas (HH) Undergoing Epilepsy Evaluation: A Retrospective Study of 16 Cases.Frontiers in neurology · 2020Article
- Epileptogenicity Maps of Intracerebral Fast Activities (60-100 Hz) at Seizure Onset in Epilepsy Surgery Candidates.Frontiers in neurology · 2019Article
- PET and ictal SPECT can be helpful for localizing epileptic foci.Current opinion in neurology · 2018Review
- Objective 3D surface evaluation of intracranial electrophysiologic correlates of cerebral glucose metabolic abnormalities in children with focal epilepsy.Human brain mapping · 2017Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveInterictal [18F]fluorodeoxyglucose-positron emission tomography (FDG-PET) is used in the presurgical evaluation of patients with drug-resistant focal epilepsy. We aimed at clarifying its relationships with ictal high-frequency oscillations (iHFOs) shown to be a relevant marker of the seizure-onset zone.
methodsWe studied the correlation between FDG-PET and epileptogenicity maps in an unselected series of 37 successive patients having been explored with stereo-electroencephalography (SEEG).
resultsAt the group level, we found a significant correlation between iHFOs and FDG-PET interictal hypometabolism only in cases of temporal lobe epilepsy. This correlation was found with HFOs, and the same comparison between FDG-PET and ictal SEEG power of lower frequencies during the same epochs did not show the same significance. SIGNIFICANCE: This finding suggests that interictal FDG-PET and ictal HFOs may share common underlying pathophysiologic mechanisms of ictogenesis in temporal lobe epilepsy, and combining both features may help to identify the seizure-onset zone.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.