Evidence map›Paper›PMID 27861736›Full record

Observational studyBritish journal of haematology2016

Real-world clinical experience in the Connect

Anthony Mato, Chadi Nabhan, Neil E Kay, Mark A Weiss, Nicole Lamanna, Thomas J Kipps, David L Grinblatt, Ian W Flinn, Mark F Kozloff, Christopher R Flowers and 6 more

Registry-linked trialOpen access · hybridAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in British journal of haematology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01081015 (Connect™ CLL), which is not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01081015 completednot on this map

Connect™ CLL: The Chronic Lymphocytic Leukemia Disease Registry

TypeobservationalSponsorCelgeneRan2010 to 2017Enrolled1,494ConditionsChronic Lymphocytic Leukemia
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Trial
  3. How Do We Manage Chronic Lymphocytic Leukemia in India.Current hematologic malignancy reports · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 1 country.

Anthony MatoCenter for CLL, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA.
Chadi NabhanUniversity of Chicago, Chicago, IL, USA.
Neil E KayDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Mark A WeissThomas Jefferson University, Philadelphia, PA, USA.
Nicole LamannaLeukemia Service, Hematologic Malignancies Section, Department of Medicine, New York-Presbyterian/Columbia University Medical Center, New York, NY, USA.
Thomas J KippsUCSD, Moores Cancer Center, La Jolla, CA, USA.
David L GrinblattNorthShore University Health System, Evanston, IL, USA.
Ian W FlinnSarah Cannon Research Institute/Tennessee Oncology PLLC, Nashville, TN, USA.
Mark F KozloffSection of Oncology/Hematology, Ingalls Hospital, Harvey, IL, USA.
Christopher R FlowersEmory University, Atlanta, GA, USA.
Charles M FarberCarol G. Simon Cancer Center, Morristown Memorial Hospital, Morristown, NJ, USA.
Pavel KiselevCelgene Corporation, Summit, NJ, USA.
Arlene S SwernCelgene Corporation, Summit, NJ, USA.
Kristen SullivanCelgene Corporation, Overland Park, KS, USA.
E Dawn FlickCelgene Corporation, San Francisco, CA, USA.
Jeff P SharmanWillamette Valley Cancer, US Oncology, Springfield, OR, USA.
Columbia University Irving Medical Center · USEmory University · USMayo Clinic in Arizona · USMoores Cancer CenterMorristown Medical Center · USNorthShore University HealthSystem · USSarah Cannon · USThomas Jefferson University · USUniversity of Chicago · USUniversity of Illinois Chicago · USUniversity of Pennsylvania · US

Funding

Tissue CoreP01CA081534 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KIPPS, THOMAS J · 2000 to 2016
$59.5M
NCI NIH HHS P01 CA081534
6 · The paper itself

Abstract

The clinical course of chronic lymphocytic leukaemia (CLL) is heterogeneous, and treatment options vary considerably. The Connect

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellRegistriesAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsChromosome AberrationsDisease ManagementFemaleHumansMaleMiddle AgedPractice Patterns, Physicians'PrognosisProspective StudiesTreatment Outcomechemoimmunotherapychronic lymphocytic leukaemiaConnect® CLL Registrypatient characteristicspractice patterns

Identifiers

PMID27861736
PMCPMC5132115
OpenAlexW2550935748

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.