ArticlePloS one2016
Symptoms of Dry Eye Disease and Personality Traits.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Dry Eye Disease and personality: a systematic review.Frontiers in medicine · 2026Pooled it
- Assessment of Dry Eye Disease Symptoms in Health Science University Students: A Combined Approach Using CVS-Q and Schirmer Tear Test to Evaluate the Influence of Digital Devices.Clinical optometry · 2026Article
- Content validity of self-reports of excess skin after bariatric surgery: protocol for a Dutch cross-sectional study.BMJ open · 2025Article
- The Relationship Between Anxiety Sensitivity, Emotional States, and Dry Eye Disease Symptom Severity: A Cross-Sectional Study.Vision (Basel, Switzerland) · 2025Article
- Personality traits and symptoms of anxiety and depression in patients with primary vitreous floaters.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Subjective dry eye symptoms and associated factors among the national general population in China during the COVID-19 pandemic: A network analysis.Journal of global health · 2023Article
- Animal Models in Eye Research: Focus on Corneal Pathologies.International journal of molecular sciences · 2023Review
- Association between personality traits and experience of adverse periocular reactions to topical prostaglandin analogues.BMJ open ophthalmology · 2022Article
- Role of neuroticism and perceived stress on quality of life among patients with dry eye disease.Scientific reports · 2022Observational
- Association between self-reported drug hypersensitivity reactions and psychological disorders.Asia Pacific allergy · 2022Article
- Reliability, validity, and responsiveness of the Thai version of the Dry Eye-Related Quality-of-Life Score questionnaire.PloS one · 2022Article
- Provocation of dry eye disease symptoms during COVID-19 lockdown.Scientific reports · 2021Article
- Psychological contribution to understanding the nature of dry eye disease: a cross-sectional study of anxiety sensitivity and dry eyes.Health psychology and behavioral medicine · 2020Article
- Why the symptoms and objective signs of dry eye disease may not correlate.Journal of optometryReview
- The association between personality traits and dry eye disease: A cross-sectional study.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
- Personality traits neuroticism and openness as well as early abnormal eye conditions as predictors of the occurrence of eye problems in adulthood.Health psychology openArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The essential targets of dry eye disease (DED) treatments include both objective signs and subjective symptoms. However, due to the numerous subjective symptoms, it is understandable why little association has been found between the signs and symptoms. Although psychological influences on the subjective symptoms have been reported, little is known about the influence of personality traits. The present study analyzed the relationship between the signs/symptoms of DED and the personality traits of patients using a cross-sectional design. We examined 56 DED patients (mean age; 62.4 ± 12.9, range 34-85 years) visiting the outpatient clinic of the Department of Ophthalmology at the Nippon Medical School Hospital in Tokyo, Japan. Objective signs evaluated included the Schirmer I test, tear breakup time (BUT), fluorescein and lissamine green staining, and tear osmolality. Subjective symptoms were assessed by the Ocular Surface Disease Index (OSDI) and Dry Eye-Related Quality-of-Life Score (DEQS) questionnaires. For personality traits, the Big Five personality traits model analysis was used. Correlations between the objective signs, subjective symptoms, and personality traits were analyzed. A significant correlation was found between the neuroticism in the Big Five Personality Inventory and the symptoms assessed by the DEQS (r = -0.35, p < 0.01), and the OSDI (r = -0.28, p < 0.05). There was no significant correlation observed between the signs and the symptoms, or between the signs and any personality traits. The results of our current study suggest that the personality of the patient, which appears to be the basis of various psychological factors, can have some impact on the subjective symptoms. This may be one of the reasons why there has been little association noted between the signs and symptoms of DED.
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