SynthesisPloS one2016
Clinical Characteristics of Malignant Melanoma in Southwest China: A Single-Center Series of 82 Consecutive Cases and a Meta-Analysis of 958 Reported Cases.
Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Clinicopathological characteristics and prognosis of melanoma: A retrospective cohort study in Xinjiang, China.PloS one · 2026Article
- Unmet needs and associated factors among patients with melanoma: a mixed-methods study.Frontiers in public health · 2026Article
- Endoscopic ultrasound features of rectal melanoma: A case report and review of literature.World journal of clinical cases · 2024Article
- Early time to recurrence predicts worse survival in patients with localized or regionally advanced cutaneous melanoma.Dermatologic therapy · 2021Article
- A Clinicopathological Analysis of Melanocytic Nevi: A Retrospective Series.Frontiers in medicine · 2021Article
- Clinical and Demographic Profile of Cutaneous Melanoma: Pakistani Perspective.World journal of plastic surgery · 2020Article
- Article
- Clinical characteristics of malignant melanoma in central China and predictors of metastasis.Oncology letters · 2020Article
- Elevated Neutrophil-to-Lymphocyte Ratio Is Associated With Poor Outcomes for Melanoma Patients Treated With PD-1 Inhibitor or Chemotherapy in a Chinese Population.Frontiers in oncology · 2020Article
- A Phase Ib Study of Pembrolizumab as Second-Line Therapy for Chinese Patients With Advanced or Metastatic Melanoma (KEYNOTE-151).Translational oncology · 2019Article
- Personal ultraviolet Radiation exposure in a cohort of Chinese mother and child pairs: the Chinese families and children study.BMC public health · 2019Article
- Malignant melanoma with indiscoverable skin manifestations presenting with paresis and refractory hypercalcemia: A case report.Medicine · 2019Article
- Skin Cancer Knowledge, Attitudes, and Practices among Chinese Population: A Narrative Review.Dermatology research and practice · 2018Review
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present study determined the clinical characteristics and prognostic factors in patients with malignant melanoma based on a series of 82 cases from January 2009 to December 2014 in Southwest Hospital and a meta-analysis (including 12 articles) involving 958 patients in China. MATERIALS AND
methodsThe database elements included basic demographic data and prognosticators which were extracted from medical records. Statistical analyses of survival, and multivariate analyses of factors associated with survival were performed using the Kaplan-Meier method, and the Cox proportional hazard model, respectively. Literatures were identified through systematic searches in PubMed, Embase, the Cochrane Library, China National Knowledge Infrastructure (CNKI) and Weipu database (VIP) database for the period from inception to December 2015. The meta-analysis was conducted using R 3.1.1 meta-analysis software.
resultsIn this series of 82 cases, the median age of the patients was 57.50 years. Melanoma was located in the foot in 79% of patients. Sixty-one patients (74.4%) were classified as stage II-III. Thirty-two patients (39.0%) had acral malignant melanoma, and 31 patients (37.8%) had nodular malignant melanoma. The clinical characteristics of melanoma were similar to those in areas outside southwest China (from results of the meta-analysis). The median survival time was 29.50 months. The 1-year, 3-year, and 5-year survival rates were 84.1%, 39.0% and 10.9%, respectively. COX regression following multi-factor analysis showed that ulcer, tumor boundary and lymph node metastasis were associated with prognosis.
conclusionsThe clinical characteristics of melanoma in Chinese were different from those in Caucasians. Ulcer, tumor margins, and lymph node metastasis were significantly associated with prognosis. Immune therapy may prolong the median survival time of patients with acral melanoma, nodular melanoma, or stage I-III disease, although these differences were not statistically significant.
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