Trial reportMedicine2016
Cardiac helical CT involving a low-radiation-dose protocol with a 100-kVp setting: Usefulness of hybrid iterative reconstruction and display preset optimization.
Trial report in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Coronary computed tomography angiography using the diluted contrast material protocol: a technique for achieving uniform coronary artery enhancement.Japanese journal of radiology · 2025Article
- Recent advances in cardiac computed tomography dose reduction strategies: a review of scientific evidence and technical developments.Journal of medical imaging (Bellingham, Wash.) · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To compare the radiation dose and image quality of retrospective electrocardiogram (ECG)-gated cardiac computed tomography (CT) between a 100-kVp protocol, hybrid iterative reconstruction (HIR), and display preset optimization and the 120-kVp protocol.We prospectively enrolled 100 patients with tachycardia or atrial fibrillation scanned retrospective ECG-gated cardiac CT. We randomly assigned 50 patients to the 120-kVp protocol and 50 patients to the 100-kVp protocol. We compared effective doses (EDs) between the two protocols. The 120-kVp images were post-processed using filtered back projection (FBP). The 100-kVp images were post-processed using FBP (100-kVp protocol) and HIR (i-100-kVp protocol). We compared attenuation of the ascending aorta, signal-to-noise ratio (SNR), and image noise between the 120-kVp, 100-kVp, and i-100-kVp protocols. We performed qualitative image analysis for the 120-kVp and i-100-kVp protocols.ED of the 100-kVp protocol (4.4 ± 0.4 mSv) was 76% lower than that of the 120-kVp protocol (18.4 ± 0.6 mSv). Attenuations of the 100-kVp (549.1 ± 73.8 HU) and i-100-kVp (550.5 ± 73.7 HU) protocols were higher than that of the120-kVp protocol (437.3 ± 55.7 HU). Image noise of the 100-kVp (53.6 ± 18.5 HU) and i-100-kVp (30.9 ± 8.6 HU) protocols were higher than that of the120-kVp protocol (23.8 ± 5.7 HU). There was no significant difference in SNR and the result of qualitative image analysis between the 120-kVp and i-100-kVp protocols.The 100-kVp protocol with HIR reduced the 76% radiation dose while preserving the image quality compared with the conventional 120-kVp protocol on retrospective ECG-gated cardiac CT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.