ArticleTransplantation2016
Are Octogenarians With End-Stage Renal Disease Candidates for Renal Transplantation?
Article in Transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Kidney Transplantation in Advanced Octogenarians: The World's Oldest Kidney Transplant Recipient.Canadian journal of kidney health and disease · 2026Article
- Barriers Limiting Equity in Access to Pretransplant Evaluation Among Predialysis Patients: A Cohort Study.Transplantation direct · 2025Article
- Infection Risk in Older Kidney Transplant Recipients: An Analysis in the Era of Expanded Age Limits.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Kidney Transplantation in Older Recipients Regarding Surgical and Clinical Complications, Outcomes, and Survival: A Literature Review.Geriatrics (Basel, Switzerland) · 2024Review
- Kidney Transplant Outcomes in Elderly Population: A Systematic Review and Meta-analysis.European urology open science · 2023Review
- Distinct phenotypes of kidney transplant recipients aged 80 years or older in the USA by machine learning consensus clustering.BMJ surgery, interventions, & health technologies · 2023Article
- Poor Physical Function Trajectory Predicts Impaired Patient Survival in Older Recipients of Deceased Donor Kidneys: A Prospective Cohort Study.Transplantation direct · 2022Article
- Rethinking Chronic Kidney Disease in the Aging Population.Life (Basel, Switzerland) · 2022Review
- Progress and Recent Advances in Solid Organ Transplantation.Journal of clinical medicine · 2022Article
- A Comorbidity Index and Pretransplant Physical Status Predict Survival in Older Kidney Transplant Recipients: A National Prospective Study.Transplantation direct · 2022Article
- Outcomes in older kidney recipients from older donors: A propensity score analysis.Frontiers in nephrology · 2022Article
- Factors Influencing Long-Term Patient and Allograft Outcomes in Elderly Kidney Transplant Recipients.Kidney international reports · 2021Article
- Logistic Regression Model in a Machine Learning Application to Predict Elderly Kidney Transplant Recipients with Worse Renal Function One Year after Kidney Transplant: Elderly KTbot.Journal of aging research · 2020Article
- Improved Health-Related Quality of Life in Older Kidney Recipients 1 Year After Transplantation.Transplantation direct · 2018Article
- Proceedings From the Symposium on Kidney Disease in Older People: Royal Society of Medicine, London, January 19, 2017.Gerontology & geriatric medicineArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundElderly patients are the fastest-growing group in need of renal transplantation. This study puts focus on renal transplant recipients in their 80th year or longer at time of engraftment. Is there evidence to support an absolute upper age limit for renal transplantation?
methodsRecipients in their 80th year or longer, transplanted between 1983 and 2015, were included. Data were retrieved from the Norwegian Renal Registry in the end of October 2015. Graft and patient survivals were compared with recipients aged 70 to 79 years at transplantation.
resultsForty-seven patients older than 79 years were transplanted in the defined period. Median age 80.1 years, 81% were men. Median time on dialysis before transplantation was 18.5 months. All patients received an allograft from a deceased donor (median donor age, 61.8 years). In the death-censored graft survival model, there was no statistical difference between the groups. We found improved patient and graft survivals after introduction of mycophenolate mofetil and induction with basiliximab. Patients transplanted before 2000 had increased risk of death compared with those transplanted after 2000 (hazard ratio, 3.2; 95% confidence interval, 1.2-8.7). Median uncensored graft survival for patients transplanted after the year 2000 was 5.0 year (95% confidence interval, 2.4-7.6). Median patient survival was 5.0 years (3.1-6.9) and 5-year patient survival was 55%.
conclusionsAge by itself should not be an absolute contraindication against renal transplantation. An estimated 5-year survival rate of 55% post-engraftment for an 80-year-old patient is in our opinion more than acceptable.
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