Evidence map›Paper›PMID 27860313›Full record

ArticleInfluenza and other respiratory viruses2017

Origin, distribution, and potential risk factors associated with influenza A virus in swine in two production systems in Guatemala.

Ana S Gonzalez-Reiche, Ana L Ramírez, María L Müller, David Orellana, Silvia M Sosa, Pablo Ola, Jorge Paniagua, Lucía Ortíz, Jorge Hernandez, Celia Cordón-Rosales and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Influenza and other respiratory viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Ana S Gonzalez-ReicheDepartment of Population Health, Poultry Diagnostic and Research Center Athens, University of Georgia, Athens, GA, USA.
Ana L RamírezUniversidad del Valle de Guatemala, Guatemala City, Guatemala.
María L MüllerDepartment of Population Health, Poultry Diagnostic and Research Center Athens, University of Georgia, Athens, GA, USA.
David OrellanaMinisterio de Agricultura Ganadería y Alimentación, Guatemala city, Guatemala.
Silvia M SosaUniversidad del Valle de Guatemala, Guatemala City, Guatemala.
Pablo OlaMinisterio de Agricultura Ganadería y Alimentación, Guatemala city, Guatemala.
Jorge PaniaguaUniversidad del Valle de Guatemala, Guatemala City, Guatemala.
Lucía OrtízUniversidad del Valle de Guatemala, Guatemala City, Guatemala.
Jorge HernandezUniversity of Florida, Gainesville, FL, USA.
Celia Cordón-RosalesUniversidad del Valle de Guatemala, Guatemala City, Guatemala.
Daniel R PerezDepartment of Population Health, Poultry Diagnostic and Research Center Athens, University of Georgia, Athens, GA, USA.
Universidad del Valle de Guatemala · GTMinistry of Public Health and Social Assistance · GTUniversity of Florida · USUniversity of Georgia · USU.S. National Poultry Research Center · US

Funding

NIAID NIH HHS HHSN266200700010CNIAID NIH HHS HHSN272201400008C
6 · The paper itself

Abstract

backgroundGuatemala is the country with the largest swine production in Central America; however, evidence of influenza A virus (IAV) in pigs has not been clearly delineated.

objectivesIn this study, we analyzed the presence and spatial distribution of IAV in commercial and backyard swine populations.

methodsSamples from two nationwide surveys conducted in 2010 and 2011 were tested using virological (rRT-PCR and virus isolation) and serological (ELISA and hemagglutination inhibition) assays to detect IAV.

resultsInfluenza A virus was detected in 15.7% of the sampled pigs (30.6% of herds) in 2010 and in 11.7% (24.2% of herds) in 2011. The percentage of seropositive pigs was 10.6% (16.1% of herds) and 1.4% (3.1% of herds) for each year, respectively. Three pandemic H1N1 and one seasonal human-like H3N2 viruses were isolated. Antibodies against viruses from different genetic clusters were detected. No reassortant strains with swine viruses were detected. The H3N2 virus was closely related to human viruses that circulated in Central America in 2010, distinct to the most recent human seasonal vaccine lineages. Spatial clusters of rRT-PCR positive herds were detected each year by scan statistics.

conclusionsOur results demonstrate circulation of IAV throughout Guatemala and identify commercial farms, animal health status, and age as potential risk factors associated with IAV infection and exposure. Detection of human-origin viruses in pigs suggests a role for humans in the molecular epidemiology of IAV in swine in Guatemala and evidences gaps in local animal and human surveillance.

Indexed as

AnimalsAntibodies, ViralEnzyme-Linked Immunosorbent AssayGuatemalaHemagglutination Inhibition TestsHemagglutinin Glycoproteins, Influenza VirusHumansInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza, HumanLivestockOrthomyxoviridae InfectionsPhylogenyRisk FactorsSpatial AnalysisSwineAntibodies, ViralHemagglutinin Glycoproteins, Influenza VirusCentral AmericaepidemiologyfarmGuatemalainfluenza A virusphylogenyspatial analysisswine

Identifiers

PMID27860313
PMCPMC5304577
OpenAlexW2551980039

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.