ArticleHuman brain mapping2017
A statistical framework for neuroimaging data analysis based on mutual information estimated via a gaussian copula.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 156 papers.
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Who cites it
156 citing papers in PubMed.
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- Dynamic facial movements shape how confident speakers appear.Proceedings. Biological sciences · 2026Article
- Estimating Mutual Information and Pearson Correlation on Neural Evoked Responses.Neuroinformatics · 2026Article
- Attentional selection drives information convergence within macaque lateral prefrontal cortex.PNAS nexus · 2026Article
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- Functional muscle networks as biomarkers of post-stroke motor impairment and therapeutic responsiveness.eLife · 2026Article
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- Metabolism-weighted brain connectome reveals synaptic integration and vulnerability to neurodegeneration.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Pupil- and gaze dynamics track emotion content in naturalistic speech.Scientific reports · 2026Article
- Spatially Masked Regression Reveals Local and Distributed Predictability in Electrophysiological Recordings.ArXiv · 2026Article
- Genetic risk of Alzheimer's disease is associated with loss of brain network segregation in midlife.Communications biology · 2026Article
- Clarifying the conceptual dimensions of representation in neuroscience.Nature reviews. Neuroscience · 2026Review
- Broadband synergy versus oscillatory redundancy in the visual cortex.Nature communications · 2026Article
- Delayed, Reduced, and Redundant: Information Processing of Prediction Errors during Human Sleep.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Towards an informational account of interpersonal coordination.Nature reviews. Neuroscience · 2026Review
- Lower resting-state EEG mean eigenvector centrality is associated with higher math anxiety.Frontiers in human neuroscience · 2026Article
- Higher integration of the whole-brain resting state theta band network is associated with spatial working memory.Frontiers in human neuroscience · 2026Article
- THOI: An efficient and accessible library for computing higher-order interactions enhanced by batch-processing.PloS one · 2026Article
96 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
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Abstract
We begin by reviewing the statistical framework of information theory as applicable to neuroimaging data analysis. A major factor hindering wider adoption of this framework in neuroimaging is the difficulty of estimating information theoretic quantities in practice. We present a novel estimation technique that combines the statistical theory of copulas with the closed form solution for the entropy of Gaussian variables. This results in a general, computationally efficient, flexible, and robust multivariate statistical framework that provides effect sizes on a common meaningful scale, allows for unified treatment of discrete, continuous, unidimensional and multidimensional variables, and enables direct comparisons of representations from behavioral and brain responses across any recording modality. We validate the use of this estimate as a statistical test within a neuroimaging context, considering both discrete stimulus classes and continuous stimulus features. We also present examples of analyses facilitated by these developments, including application of multivariate analyses to MEG planar magnetic field gradients, and pairwise temporal interactions in evoked EEG responses. We show the benefit of considering the instantaneous temporal derivative together with the raw values of M/EEG signals as a multivariate response, how we can separately quantify modulations of amplitude and direction for vector quantities, and how we can measure the emergence of novel information over time in evoked responses. Open-source Matlab and Python code implementing the new methods accompanies this article. Hum Brain Mapp 38:1541-1573, 2017. © 2016 Wiley Periodicals, Inc.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.