ArticleAddiction biology2018
Impact of alcohol use on EEG dynamics of response inhibition: a cotwin control analysis.
Article in Addiction biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Effects of Alcohol on EEG Activity: A Systematic Review Focused on Sex-Related Differences in Youth.Current neuropharmacology · 2025Pooled it
- Oscillatory and behavioral indices of cognitive control dysregulation in young adult binge drinkers are influenced by sex differences.Alcohol, clinical & experimental research · 2026Article
- Adolescent Risky Alcohol Use Is Associated With Electrophysiological Markers of Error Processing: Findings From a Large Cohort Study.Biological psychiatry global open science · 2026Article
- Clarifying the place of p300 in the empirical structure of psychopathology over development.Journal of psychopathology and clinical science · 2024Article
- Testing the consequences of alcohol, cannabis, and nicotine use on hippocampal volume: a quasi-experimental cotwin control analysis of young adult twins.Psychological medicine · 2023Article
- The Effects of Alcohol and Cannabis Use on the Cortical Thickness of Cognitive Control and Salience Brain Networks in Emerging Adulthood: A Co-twin Control Study.Biological psychiatry · 2021Article
- Parietal P3 and midfrontal theta prospectively predict the development of adolescent alcohol use.Psychological medicine · 2021Article
- Neurocognitive performance in alcohol use disorder using the NIH toolbox: Role of severity and sex differences.Drug and alcohol dependence · 2020Article
- Neurobiology and the Hierarchical Taxonomy of Psychopathology: progress toward ontogenetically informed and clinically useful nosology .Dialogues in clinical neuroscience · 2020Review
- Using a co-twin control design to evaluate alternative trait measures as indices of liability for substance use disorders.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2020Article
- Theta oscillations in prolactinomas: Neurocognitive deficits in executive controls.NeuroImage. Clinical · 2020Article
- Neuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment?Frontiers in psychiatry · 2020Review
- Minnesota Center for Twin and Family Research.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019Article
- Conflict-related medial frontal theta as an endophenotype for alcohol use disorder.Biological psychology · 2018Article
- The utility of twins in developmental cognitive neuroscience research: How twins strengthen the ABCD research design.Developmental cognitive neuroscience · 2018Review
- Problematic alcohol use and hippocampal volume in a female sample: disentangling cause from consequence using a co-twin control study design.Psychological medicine · 2018Article
- Testing the effects of adolescent alcohol use on adult conflict-related theta dynamics.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Research indicates that alcohol misuse is associated with behavioral disinhibition, but the neurophysiological mechanisms governing this relationship remain largely unknown. Recent work suggests that successful inhibition and cognitive control involve electrophysiological theta-band dynamics, including medial frontal cortex (MFC) power enhancement and functional connectivity between the MFC and dorsal prefrontal cortex (dPFC) regions, which may be disrupted by alcohol misuse. In addition, research suggests that, compared to men, women are at heightened risk of experiencing the negative physical and neurocognitive correlates of drinking. The present study tested the hypothesis that alcohol misuse has a deleterious effect on theta-band response inhibition EEG dynamics in a sample of 300 24-year-old same-sex twins. A cotwin control (CTC) design was used to disentangle premorbid risk for alcohol use from the causal effects of alcohol exposure. Drinking was negatively associated with theta-band MFC power and MFC-dPFC connectivity during response inhibition, and this effect was stronger among women. The CTC analysis suggested that, for women, reduced nogo-related theta-band MFC power and MFC-dPFC connectivity were both consistent with the potential deleterious causal effects of alcohol exposure. These findings suggest that diminished theta-band MFC power and MFC-dPFC connectivity may be neurophysiological mechanisms underlying alcohol-related disinhibition. Although preliminary, these results suggest that normative levels of alcohol use during emerging adulthood have potential sex-specific causal effects on response inhibition EEG dynamics, and thus have potentially significant public health implications.
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Registered trials
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