Trial reportExperimental physiology2017
Does attenuated skin blood flow lower sweat rate and the critical environmental limit for heat balance during severe heat exposure?
Trial report in Experimental physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Caffeine ingestion compromises thermoregulation and does not improve cycling time to exhaustion in the heat amongst males.European journal of applied physiology · 2024Trial
- Epidemiology, mechanisms and clinical implications of heat-related kidney disease.Nature reviews. Nephrology · 2026Review
- Comparison of heat acclimation after once daily and thrice daily heat exposures in healthy adults.Physiological reports · 2026Article
- No effect of stage 1 hypertension or hypertensive medication on critical environmental limits (PSU HEAT Project).American journal of physiology. Heart and circulatory physiology · 2025Article
- The effect of prescription and over-the-counter medications on core temperature in adults during heat stress: a systematic review and meta-analysis.EClinicalMedicine · 2024Article
- Experimental research in environmentally induced hyperthermic older persons: A systematic quantitative literature review mapping the available evidence.Temperature (Austin, Tex.) · 2024Article
- A century of exercise physiology: concepts that ignited the study of human thermoregulation. Part 3: Heat and cold tolerance during exercise.European journal of applied physiology · 2024Review
- Coexisting metabolic dysfunction-associated steatotic liver disease exacerbates in-hospital outcomes in patients with heat stroke.Frontiers in medicine · 2024Article
- Effect of reflex and mechanical decreases in skin perfusion on thermal- and agonist-induced eccrine sweating in humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Article
- Heat stress vulnerability and critical environmental limits for older adults.Communications earth & environment · 2023Article
- Thermal strain is greater in the late afternoon than morning during exercise in the gym without airflow and air conditioning on a clear summer day.Frontiers in sports and active living · 2023Article
- Human temperature regulation under heat stress in health, disease, and injury.Physiological reviews · 2022Review
- Stress Response and Safe Driving Time of Bus Drivers in Hot Weather.International journal of environmental research and public health · 2022Article
- Exertional heat stroke: pathophysiology and risk factors.BMJ medicine · 2022Review
- Correlation of neurological level and sweating level of injury in persons with spinal cord injury.The journal of spinal cord medicine · 2021Observational
- Methods for improving thermal tolerance in military personnel prior to deployment.Military Medical Research · 2020Review
- Keeping older individuals cool in hot and moderately humid conditions: wetted clothing with and without an electric fan.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Cuff inflation time significantly affects blood flow recorded with venous occlusion plethysmography.European journal of applied physiology · 2019Article
- Folic acid supplementation does not attenuate thermoregulatory or cardiovascular strain of older adults exposed to extreme heat and humidity.Experimental physiology · 2018Article
- Free-living, continuous hypo-hydration, and cardiovascular response to exercise in a heated environment.Physiological reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
Abstract
NEW
findingsWhat is the central question of this study? Does attenuated skin blood flow diminish sweating and reduce the critical environmental limit for heat balance, which indicates maximal heat loss potential, during severe heat stress? What is the main finding and its importance? Isosmotic hypovolaemia attenuated skin blood flow by ∼20% but did not result in different sweating rates, mean skin temperatures or critical environmental limits for heat balance compared with control and volume-infusion treatments, suggesting that the lower levels of skin blood flow commonly observed in aged and diseased populations may not diminish maximal whole-body heat dissipation. Attenuated skin blood flow (SkBF) is often assumed to impair core temperature (T
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.