Evidence map›Paper›PMID 27859831›Full record

ArticleMolecular reproduction and development2016

Albinism as a visual, in vivo guide for CRISPR/Cas9 functionality in the sea urchin embryo.

Nathalie Oulhen, Gary M Wessel

Abstract readLetter
In one paragraph

Article in Molecular reproduction and development, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. The tuxedo sea urchinbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. CRISPR/Cas9 knockin methodology for the sea urchin embryo.Molecular reproduction and development · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Embryo microinjection of the lecithotrophic sea urchinJournal of biological methods · 2019
    Article
  15. Review
  16. Review
  17. Single nucleotide editing without DNA cleavage using CRISPR/Cas9-deaminase in the sea urchin embryo.Developmental dynamics : an official publication of the American Association of Anatomists · 2017
    Article
  18. Transient translational quiescence in primordial germ cells.Development (Cambridge, England) · 2017
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nathalie OulhenDepartment of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, Rhode Island.
Gary M WesselDepartment of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, Rhode Island.

Funding

Post-translational Regulation of Germline DeterminantsR01HD028152 · NICHD · BROWN UNIVERSITY · PI WESSEL, GARY M · 1997 to 2016
$3.9M
Mechanisms of quiescence in primordial germ cellsR01GM125071 · NIGMS · BROWN UNIVERSITY · PI WESSEL, GARY M · 2017 to 2020
$1.4M
NICHD NIH HHS R01 HD028152NIGMS NIH HHS R01 GM125071
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AlbinismCRISPR-Cas SystemsAnimalsSea Urchins

Identifiers

PMID27859831
PMCPMC6430563

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.