Evidence map›Paper›PMID 27859632›Full record

ArticleJournal of clinical laboratory analysis2017

The establishment of biological reference intervals of nontraditional glycemic markers in a Chinese population.

Qiang Zhou, De-Bao Shi, Li-Ying Lv

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Qiang ZhouDepartment of Clinical Laboratory, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
De-Bao ShiDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Li-Ying LvDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe established the reference intervals for glycated albumin (GA), fructosamine (FA), and 1,5-anhydroglucitol (1,5-AG) in a Chinese healthy population.

methodsThis study enrolled a total of 458 eligible reference individuals, consisted of 226 men and 232 women, aged from 20~79 years (median age 43 years), who attending routine healthy checks. We stratified the subjects according to gender (males and females) and age (20-39, 40-59, and 60-79 years), and combined statistical methods with Lahti algorithm, as well as appropriate clinical consideration, to judge whether partitioning for data was needed.

resultsGlycated albumin levels between males and females were statistically different (P<.001), but the absolute difference between the upper reference limits was only 0.31%, which was too small to be clinically relevant. GA levels across the three age groups were statistically different (P<.001), and Lahti algorithm suggested partitioning for 20-59 and 60-79 years, which reference intervals were 10.38%-13.89% and 10.23%-14.79%, respectively. 1,5-AG levels in males were significant higher than females (P<.001), and absolute difference was 51 μmol/L (8.5 μg/mL) in mean level. Thus, partitioning for gender was needed. Reference intervals for 1,5-AG were 107-367 μmol/L for males and 79-306 μmol/L for females. The absolute difference of the lower reference limits for FA was only 7 μmol/L between males and females. FA levels across the three age groups were not statistically different (P>.05). The reference interval for FA was 220-298 μmol/L.

conclusionNew reference intervals for nontraditional glycemic markers were established based on a Chinese population.

Indexed as

Blood Chemical AnalysisAdultAgedAsian PeopleBiomarkersBlood GlucoseDeoxyglucoseFemaleFructosamineGlycated Serum AlbuminGlycation End Products, AdvancedHumansMaleMiddle AgedReference ValuesSerum Albumin1,5-anhydroglucitolBiomarkersBlood GlucoseDeoxyglucoseFructosamineGlycated Serum AlbuminGlycation End Products, AdvancedSerum Albumin1,5-anhydroglucitolfructosamineglycated albuminreference intervals

Identifiers

PMID27859632
PMCPMC6816948
OpenAlexW2556640877

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.