ArticleJournal of surgical oncology2017
Impact of pancreatectomy on long-term patient-reported symptoms and quality of life in recurrence-free survivors of pancreatic and periampullary neoplasms.
Article in Journal of surgical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- The Role of Specialty Palliative Care in Elective Surgical Oncology: A Systematic Review.Annals of surgical oncology · 2025Pooled it
- Gastrointestinal symptoms and health-related quality of life before and after pancreatectomy for pancreatic cancer (GO-PANC): longitudinal nationwide study.The British journal of surgery · 2026Article
- Fatigue and diabetes self-management among operable pancreatic cancer survivors with comorbid diabetes: comparative propensity analysis.Journal of cancer survivorship : research and practice · 2025Article
- Prevalence of Psychological Symptoms in Patients Undergoing Pancreatoduodenectomy and Results of a Distress Management System: A Clinic-Based Study.Cancer research and treatment · 2022Article
- The patient's perspective: a qualitative study of individual experience with decision-making, treatment, and recovery for resectable pancreatic cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Factors Influencing Exercise Following Pancreatic Tumor Resection.Annals of surgical oncology · 2021Article
- Long-Term Assessment of Pancreatic Function After Pancreatectomy for Cystic Neoplasms.The Journal of surgical research · 2020Article
- Physical activity and exercise during preoperative pancreatic cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
- Progression to pancreatic ductal adenocarcinoma from pancreatic intraepithelial neoplasia: Results of a simulation model.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2018Article
- Long-term Quality of Life and Gastrointestinal Functional Outcomes After Pancreaticoduodenectomy.Annals of surgery · 2018Article
- Association between chronological depressive changes and physical symptoms in postoperative pancreatic cancer patients.BioPsychoSocial medicine · 2018Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundLong term patient-reported symptoms and quality of life (QOL) are important outcome metrics following cancer operations, but have been poorly described in patients who have previously undergone pancreatectomy.
methodsWe conducted a cross-sectional survey of recurrence-free survivors of pancreatic ductal adenocarcinoma, periampullary carcinomas, and pancreatic neuroendocrine tumors who had undergone prior pancreatectomy. QOL and symptom burden were measured using the Functional Assessment of Cancer Therapy-Hepatobiliary Questionnaire, and psychosocial distress was measured using the Hospital Anxiety and Depression Scale.
resultsOf 331 eligible patients surveyed, 217 (66%) participated at a median of 53.3 (range, 7.6-214.8) months following pancreatoduodenectomy (PD, n = 165) or distal pancreatectomy (DP, n = 52). Among all patients, overall QOL scores were favorable and influenced by race, histology, and type of surgery. The most common significant symptoms reported were fatigue (82%), back pain (32%), and difficulty with digestion (31%). In general, PD survivors reported better QOL, lower levels of anxiety/depression, greater levels of diarrhea, and improved appetite, constipation, fatigue, anxiety, and depression (P < 0.05) than DP survivors. On both univariate and multivariate regression analysis, DP was negatively associated with QOL.
conclusionsMost disease-free survivors of pancreatic neoplasms report favorable QOL, but gastrointestinal and psychosocial symptoms may exist long after pancreatectomy. J. Surg. Oncol. 2017;115:144-150. © 2016 Wiley Periodicals, Inc.
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