Evidence map›Paper›PMID 27859043›Full record

ArticleEuropean journal of immunology2017

Monocyte-derived dendritic cells enhance protection against secondary influenza challenge by controlling the switch in CD8

Jazmina L G Cruz, José V Pérez-Girón, Anja Lüdtke, Sergio Gómez-Medina, Paula Ruibal, Juliana Idoyaga, César Muñoz-Fontela

Open access · hybridAbstract read
In one paragraph

Article in European journal of immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Jazmina L G CruzHeinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
José V Pérez-GirónHeinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Anja LüdtkeHeinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Sergio Gómez-MedinaHeinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Paula RuibalHeinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Juliana IdoyagaDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
César Muñoz-FontelaHeinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.
Leibniz Institute of Virology (LIV) · DEBernhard Nocht Institute for Tropical Medicine · DEGerman Center for Infection Research · DEStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza virus infection triggers an increase in the number of monocyte-derived dendritic cells (moDCs) in the respiratory tract, but the role of these cells during antiviral immunity is still unclear. Here we show that during influenza infection, moDCs dominate the late activation of CD8

Indexed as

T-Cell Antigen Receptor SpecificityAnimalsCD8-Positive T-LymphocytesCells, CulturedDendritic CellsImmunodominant EpitopesImmunologic MemoryInfluenza A Virus, H1N1 SubtypeLungLymphocyte ActivationMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutMice, TransgenicMonocytesImmunodominant EpitopesViral Core ProteinsCD8+ T cell · Dendritic cell · Immunodominance · Influenza virus · Monocyte

Identifiers

PMID27859043
PMCPMC5324604
OpenAlexW2549469016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.