Evidence map›Paper›PMID 27858911›Full record

ArticleMedicine2016

Increased risk of depression in patients with acquired sensory hearing loss: A 12-year follow-up study.

Wei-Ting Hsu, Chih-Chao Hsu, Ming-Hsun Wen, Hong-Ching Lin, Hsun-Tien Tsai, Peijen Su, Chi-Te Sun, Cheng-Li Lin, Chung-Yi Hsu, Kuang-Hsi Chang and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
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  5. Effectiveness of a Self-Fitting Tool for User-Driven Fitting of Hearing Aids.International journal of environmental research and public health · 2021
    Trial
  6. The association between hearing impairment and incident depression in older adults: a longitudinal analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Wei-Ting HsuDepartment of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung Department of Otorhinolaryngology and Head and Neck Surgery, Mackay Memorial Hospital, Taipei Department of Otorhinolaryngology and Head and Neck Surgery, Far Eastern Memorial Hospital, New Taipei City Department of Audiology and Speech-Language Pathology, Mackay Medical College Department of Family Medicine, Mackay Memorial Hospital, Taipei Fu Jen Catholic University Graduate Institution of Business Administration Management Office for Health Data, China Medical University Hospital Graduate Institute of Clinical Medical Sciences, Center College of Medicine Department of Public Health, China Medical University, Taichung Institute of Biomedical Sciences, Mackay Medical College, Taipei, Taiwan.
Chih-Chao Hsu
Ming-Hsun Wen
Hong-Ching Lin
Hsun-Tien Tsai
Peijen Su
Chi-Te Sun
Cheng-Li Lin
Chung-Yi Hsu
Kuang-Hsi Chang
Yi-Chao Hsu
Kaohsiung Veterans General Hospital · TWInstitute of Clinical Research · USMackay Medical College · TWChina Medical University · CNFar Eastern Memorial Hospital · TWFu Jen Catholic University · TWMackay Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acquired sensory hearing loss (SHL) is suggested to be associated with depression. However, some studies have reported conflicting results. Our study investigated the relationship between the prevalence of SHL and the incidence of depression over 12 years of follow-up by using data from the Taiwan National Health Insurance Research Database (NHIRD). We sought to determine the association between SHL and subsequent development of depression and discuss the pathophysiological mechanism underlying the association.Patients with SHL were identified from the NHIRD (SHL cohort). A non-SHL cohort, comprising patients without SHL frequency-matched with the SHL patients according to age group, sex, and the year of diagnosis of SHL at the ratio of 1:4, was constructed, and the incidence of depression was evaluated in both cohorts. A multivariable model was adjusted for age, sex, and comorbidity.The SHL cohort and non-SHL cohort comprised 5043 patients with SHL and 20,172 patients without SHL, respectively. The incidences density rates were 9.50 and 4.78 per 1000 person-years in the SHL cohort and non-SHL cohort, respectively. After adjustment for age, sex, and comorbidities, the risk of depression was higher in the SHL cohort than in the non-SHL cohort (hazard ratio = 1.73, 95% confidence interval = 1.49-2.00).Acquired SHL may increase the risk of subsequent depression. The results demonstrated that SHL was an independent risk factor regardless of sex, age, and comorbidities. Moreover, a strong association between hearing loss and subsequent depression among Taiwanese adults of all ages, particularly those aged ≤49 and >65 years and without using steroids for the treatment of SHL was observed. Prospective clinical and biomedical studies on the relationship between hearing loss and depression are warranted for determining the etiopathology.

Indexed as

AdultAgedCohort StudiesDepressionFemaleFollow-Up StudiesHearing Loss, SensorineuralHumansIncidenceMaleMiddle AgedRisk AssessmentTime Factors

Identifiers

PMID27858911
PMCPMC5591159
OpenAlexW2547750566

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.