Evidence map›Paper›PMID 27858277›Full record

ArticleEnvironmental science and pollution research international2017

First characterization of the endocrine-disrupting potential of indoor gaseous and particulate contamination: comparison with urban outdoor air (France).

Lucie Oziol, Fabrice Alliot, Jérémie Botton, Maya Bimbot, Viviane Huteau, Yves Levi, Marc Chevreuil

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. In Vitro Effects of Particulate Matter Associated with a Wildland Fire in the North-West of Italy.International journal of environmental research and public health · 2021
    Article
  7. Review
  8. Article
  9. Review
  10. Overview of air pollution and endocrine disorders.International journal of general medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucie OziolEcologie Systématique Evolution, University of Paris-Sud, CNRS, AgroParisTech, Université Paris-Saclay, 91400, Orsay, France. lucie.oziol@u-psud.fr.ORCID http://orcid.org/0000-0001-5092-084X
Fabrice AlliotSorbonne Universités, UPMC Univ Paris 06, CNRS, EPHE, UMR 7619 Metis, 4 place Jussieu, 75005, Paris, France.
Jérémie BottonINSERM, UMR1153 Epidemiology and Biostatistics Sorbonne Paris Cité Center (CRESS), Team "Early Origin of the Child's Health and Development" (ORCHAD), Paris Descartes University, Paris, France.
Maya BimbotEcologie Systématique Evolution, University of Paris-Sud, CNRS, AgroParisTech, Université Paris-Saclay, 91400, Orsay, France.
Viviane HuteauEcologie Systématique Evolution, University of Paris-Sud, CNRS, AgroParisTech, Université Paris-Saclay, 91400, Orsay, France.
Yves LeviEcologie Systématique Evolution, University of Paris-Sud, CNRS, AgroParisTech, Université Paris-Saclay, 91400, Orsay, France.
Marc ChevreuilSorbonne Universités, UPMC Univ Paris 06, CNRS, EPHE, UMR 7619 Metis, 4 place Jussieu, 75005, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The composition of endocrine-disrupting compounds (EDCs) in the ambient air of indoor environments has already been described, but little is known about the inherent endocrine-disrupting potential of indoor air contamination. We therefore aimed to study the distribution of bioactive EDCs in the gaseous and particulate phases of indoor air using a cellular bioassay approach that integrates the interaction effects between chemicals. Organic air extracts, both gaseous and particulate, were taken from three indoor locations (office, apartment, and children's day care) in France and sampled in two different seasons in order to study their interference with the signaling of estrogen, androgen, and thyroid receptors. The experiments were also conducted on aerial extracts from an outdoor site (urban center). We found that gaseous and/or particulate extracts from all locations displayed estrogenicity, anti-androgenicity, and thyroidicity. Overall, indoor air extracts had a higher endocrine-disrupting potential compared to outdoor ones, especially during winter and in the day care. The biological activities were predominant for the gaseous extracts and tended to increase for the particulate extracts in cool conditions. In conclusion, our data confirmed the presence of bioactive EDCs in a gaseous state and highlighted their indoor origin and concentration, especially in the cold season.

Indexed as

Air PollutantsAir Pollution, IndoorEndocrine DisruptorsEnvironmental MonitoringFranceGasesHumansParticulate MatterSeasonsAir PollutantsEndocrine DisruptorsGasesParticulate MatterAnti-androgenicityBioassayEndocrine disruptorsEstrogenicityGaseous phaseIndoor airParticulate phaseThyroidicity

Identifiers

PMID27858277

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.