Evidence map›Paper›PMID 27858264›Full record

ArticleThe protein journal2016

Purification and Characterization of Lactate Dehydrogenase in the Foot Muscle and Hepatopancreas of Otala lactea.

Isabelle A MacLean, Amanda M S Mattice, Nadine J Adam, Kenneth B Storey

Abstract read
PubMed Publisher
In one paragraph

Article in The protein journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Purification and characterization of a urea sensitive lactate dehydrogenase from skeletal muscle of the African clawed frog, Xenopus laevis.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2019
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Isabelle A MacLean, 1125 Colonel By Dr, Ottawa, ON, K1S 5B6, Canada.
Amanda M S Mattice, 1125 Colonel By Dr, Ottawa, ON, K1S 5B6, Canada.
Nadine J Adam, 1125 Colonel By Dr, Ottawa, ON, K1S 5B6, Canada.
Kenneth B Storey, 1125 Colonel By Dr, Ottawa, ON, K1S 5B6, Canada. kenneth.storey@carleton.ca.ORCID http://orcid.org/0000-0002-7363-1853
Carleton University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactate dehydrogenase (LDH) has a crucial role in maintaining ATP production as the terminal enzyme in anaerobic glycolysis. This study will determine the effect of posttranslational modifications (PTMs) on the activity of LDH in the foot muscle and hepatopancreas of an estivating snail, Otala lactea. LDH in foot muscle of O. lactea was purified to homogeneity and partially purified in hepatopancreas in a two-step and three-step process, respectively. The kinetic properties and stability of these isoforms were determined where there was a significant difference in K

Indexed as

Protein Processing, Post-TranslationalAnimalsEnzyme StabilityEstivationHepatopancreasIsoenzymesKineticsL-Lactate DehydrogenaseMusclesOrgan SpecificityPhosphorylationPyruvic AcidSnailsSubstrate SpecificityUreaIsoenzymesL-Lactate DehydrogenasePyruvic AcidUreaEnzyme regulationEstivationGlycolysisLactate dehydrogenaseOtala lacteaPosttranslational modifications

Identifiers

PMID27858264
OpenAlexW2556099291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.