ArticleThe Indian journal of radiology & imaging
Multiparametric 3T MRI evaluation of hereditary spastic paraplegia: A case report.
Article in The Indian journal of radiology & imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- "Ears of the lynx" sign on MRI: A radiologic clue to hereditary spastic paraplegia.Radiology case reports · 2026Article
- 'Ears of the Lynx' sign: an important and useful MRI clue for diagnosis of hereditary spastic paraplegia (HSP) caused by mutation in SPG 15 gene.BMJ case reports · 2021Article
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4 authors at 1 institution in 1 country.
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Abstract
Hereditary spastic paraplegia (HSP) is a rare heterogeneous group of familial neurodegenerative disorders characterized by degeneration of the corticospinal tracts and posterior column of the spinal cord. Previously described radiological findings included nonspecific brain abnormalities such as brain atrophy and white matter lesions, as well as atrophy of the corpus callosum and spinal cord. Magnetic resonance spectroscopy may reveal reduced concentrations of normal brain metabolites and elevated levels of myoinositol. Diffusion tensor imaging shows increased mean diffusivity and reduced fractional anisotropy in the periventricular white matter, which is compatible with damaged myelinated axons. We present here two cases of HSP in a single family with typical imaging findings.
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