ArticleThe Indian journal of radiology & imaging
Magnetic resonance imaging spectrum of perinatal hypoxic-ischemic brain injury.
Article in The Indian journal of radiology & imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Predictors of outcome following neonatal encephalopathy in low- and middle-income countries: a systematic review and meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Diffusion tensor imaging and MR spectroscopy in the evaluation of neonatal encephalopathies.Journal of neonatal-perinatal medicine · 2026Article
- Preserved Limbic White Matter Predicts Favorable 2-Year Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy.Annals of the Child Neurology Society · 2025Article
- Spectrum of Brain Imaging with 3T MRI for Infants with History of Perinatal Hypoxia and their Comparison with 128 Slice NCCT Images.Journal of pharmacy & bioallied sciences · 2024Article
- Vocal Cord Palsy in Hypoxic Brain Injury: A Qualitative Systematic Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Thiamine: An indispensable regulator of paediatric neuro-cardiovascular health and diseases.European journal of pediatrics · 2024Review
- Clinical-functional correlation with brain volumetry in severe perinatal asphyxia: a case report.Italian journal of pediatrics · 2024Article
- Clinical characteristics of cystic encephalomalacia in children.Frontiers in pediatrics · 2024Article
- Optic cupping secondary to periventricular leukomalacia: A potential mimic for normal pressure glaucoma.Radiology case reports · 2022Article
- The effect of sulforaphane on perinatal hypoxic-ischemic brain injury in rats.Physiological research · 2022Article
- The Effects of In Utero Fetal Hypoxia and Creatine Treatment on Mitochondrial Function in the Late Gestation Fetal Sheep Brain.Oxidative medicine and cellular longevity · 2022Article
- Magnetic Resonance Imaging Evaluation of Perinatal Hypoxic Ischemic Encephalopathy: An Institutional Experience.Journal of neurosciences in rural practice · 2022Article
- Treatment device for neonatal birth asphyxia related Hypoxic Ischemic Encephalopathy.BMC pediatrics · 2021Article
- Prediction of encephalopathy in perinatal asphyxia score: reaching the unreached.Journal of perinatal medicine · 2021Observational
- Forensic Analysis of Umbilical and Newborn Blood Gas Values for Infants at Risk of Cerebral Palsy.Journal of clinical medicine · 2021Article
- Effects of Juvenile or Adolescent Working Memory Experience and Inter-Alpha Inhibitor Protein Treatment after Neonatal Hypoxia-Ischemia.Brain sciences · 2020Article
- Brain Magnetic Resonance Findings in 117 Children with Autism Spectrum Disorder under 5 Years Old.Brain sciences · 2020Article
- Research Advances of Germinal Matrix Hemorrhage: An Update Review.Cellular and molecular neurobiology · 2019Review
- Effects of Intrauterine Inflammation on Cortical Gray Matter of Near-Term Lambs.Frontiers in pediatrics · 2018Article
- Magnetic Resonance Imaging Findings of Term and Preterm Hypoxic-Ischemic Encephalopathy: A Review of Relevant Animal Models and Correlation to Human Imaging.The open neuroimaging journal · 2018Review
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Perinatal hypoxic-ischemic brain injury results in neonatal hypoxic-ischemic encephalopathy and serious long-term neurodevelopmental sequelae. Magnetic resonance imaging (MRI) of the brain is an ideal and safe imaging modality for suspected hypoxic-ischemic injury. The pattern of injury depends on brain maturity at the time of insult, severity of hypotension, and duration of insult. Time of imaging after the insult influences the imaging findings. Mild to moderate hypoperfusion results in germinal matrix hemorrhages and periventricular leukomalacia in preterm neonates and parasagittal watershed territory infarcts in full-term neonates. Severe insult preferentially damages the deep gray matter in both term and preterm infants. However, associated frequent perirolandic injury is seen in term neonates. MRI is useful in establishing the clinical diagnosis, assessing the severity of injury, and thereby prognosticating the outcome. Familiarity with imaging spectrum and insight into factors affecting the injury will enlighten the radiologist to provide an appropriate diagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.