Evidence map›Paper›PMID 27856627›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2017

In Vivo Comparison of Tau Radioligands

Tobey J Betthauser, Patrick J Lao, Dhanabalan Murali, Todd E Barnhart, Shozo Furumoto, Nobuyuki Okamura, Charles K Stone, Sterling C Johnson, Bradley T Christian

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Imaging pathological tau in atypical parkinsonisms: A review.Clinical parkinsonism & related disorders · 2022
    Review
  13. Frontiers in aging neuroscience · 2022
    Article
  14. Review
  15. Review
  16. Voxel-based correlation ofeNeurologicalSci · 2021
    Article
  17. Review
  18. Biodistribution and Dosimetry Evaluation for a Novel Tau Tracer [Frontiers in bioengineering and biotechnology · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tobey J BetthauserDepartment of Medical Physics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin tbetthauser@wisc.edu.
Patrick J LaoDepartment of Medical Physics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.
Dhanabalan MuraliDepartment of Medical Physics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.
Todd E BarnhartDepartment of Medical Physics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.
Shozo FurumotoDivision of Radiopharmaceutical Neuroimaging, Tohoku University, Sendai, Japan.
Nobuyuki OkamuraDivision of Pharmacology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Charles K StoneDepartment of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.
Sterling C JohnsonGeriatric Research Education and Clinical Center, William S. Middleton Veterans Hospital, Madison, Wisconsin; and.
Bradley T ChristianDepartment of Medical Physics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.

Funding

Wisconsin Registry for Alzheimer's Prevention: Sex Differences in DNA MethylationR01AG027161 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Nathaniel Ark Chin, Sterling C Johnson · 2007 to 2026
$35.6M
The Longitudinal Course of Neural Function and Amyloid in People At Risk for ADR01AG021155 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Sterling C Johnson · 2004 to 2026
$27.0M
WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI SVAREN, JOHN P · 1985 to 2015
$25.2M
Wisconsin Alzheimer's Disease Research CenterP50AG033514 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI JOHNSON, JEFFREY A · 2009 to 2018
$16.2M
U.W. RADIOLOGICAL SCIENCES TRAINING PROGRAMT32CA009206 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Bryan Patrick Bednarz · 1985 to 2026
$12.1M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI POLLAK, SETH D · 2016 to 2020
$6.0M
NCI NIH HHS T32 CA009206NIA NIH HHS P50 AG033514NIA NIH HHS R01 AG021155NIA NIH HHS R01 AG027161NICHD NIH HHS P30 HD003352NICHD NIH HHS U54 HD090256
6 · The paper itself

Abstract

This study compared the in vivo imaging characteristics of tau PET ligands

Indexed as

AgedAged, 80 and overAlzheimer DiseaseAminopyridinesAniline CompoundsBiomarkersBrainFemaleHumansIsotope LabelingMaleMetabolic Clearance RateMiddle AgedMolecular ImagingPositron-Emission TomographyProtein Binding6-((3-fluoro-2-hydroxy)propoxy)-2-(4-methylaminophenyl)quinolineAminopyridinesAniline CompoundsBiomarkersQuinolinesRadiopharmaceuticalstau ProteinsTHK5351Alzheimer’s diseasepositron emission tomographyquantitationtauTHK

Identifiers

PMID27856627
PMCPMC5425312

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.