ReviewClinical microbiology reviews2017
From Q Fever to Coxiella burnetii Infection: a Paradigm Change.
Review in Clinical microbiology reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 498 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
498 citing papers in PubMed, 3 syntheses or guidelines pooled it, 968 citations in OpenAlex.
- Coxiella burnetii in Pakistan: a meta-analysis.BMC veterinary research · 2025Pooled it
- Cholecystitis associated with Q fever: case report and systematic review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Pooled it
- Coxiella burnetii infections from animals and ticks in South Africa: a systematic review.Veterinary research communications · 2024Pooled it
- Systematic review ofOne health (Amsterdam, Netherlands) · 2026Review
- Article
- ZOOJEU: Using Q fever to highlight a participatory science approach for fostering the co-design of management strategies for neglected zoonotic diseases.PLoS neglected tropical diseases · 2026Article
- What goes around comes around: updates in the study ofInfection and immunity · 2026Review
- High Seropositivity toAnimals : an open access journal from MDPI · 2026Article
- Metagenomic insights into pathogen diversity and public health risk of Haemaphysalis longicornis in Gansu Province of China.PLoS neglected tropical diseases · 2026Article
- Q Fever in Africa: A Systematic Review of Prevalence, Zoonotic Potential and Disease Burden.Public health challenges · 2026Review
- Q fever outbreak in a slaughterhouse in Brazil: description and decade-later investigation.Infection · 2026Article
- Efficacy of Inhalational Ciprofloxacin (Apulmiq) in an NHP Model of Q Fever.Antibiotics (Basel, Switzerland) · 2026Article
- Beyond Acute Infection: A Conceptual Framework Linking Zoonotic Bacterial Pathogens to Pulmonary Fibrosis and Lung Carcinogenesis.Biomedicines · 2026Review
- Human Q fever outbreak investigation and management in six European countries: a One Health compendium of practices and recommendations.CMI communications · 2026Review
- Prevalence and Risk Factors of Q Fever in Smallholder Dairy Farms in Kenya.Veterinary medicine and science · 2026Article
- Pilot metaproteomic profiling reveals bacterial diversity and potential medical and veterinary relevance of tick microbiomes in northern Algeria.Scientific reports · 2026Article
- Quantitative three-dimensional imaging ofInfection and immunity · 2026Article
- Afebrile Culture-Negative Vertebral Osteomyelitis in a Healthy Korean Male.Infection & chemotherapy · 2026Article
- Bacterial Granulomatous Lung Diseases: Radiological Findings and Differential Diagnosis.Infectious disease reports · 2026Review
- Evaluation of seroprevalence and risk factors for Q fever (Open veterinary journal · 2026Article
438 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coxiella burnetii is the agent of Q fever, or "query fever," a zoonosis first described in Australia in 1937. Since this first description, knowledge about this pathogen and its associated infections has increased dramatically. We review here all the progress made over the last 20 years on this topic. C. burnetii is classically a strict intracellular, Gram-negative bacterium. However, a major step in the characterization of this pathogen was achieved by the establishment of its axenic culture. C. burnetii infects a wide range of animals, from arthropods to humans. The genetic determinants of virulence are now better known, thanks to the achievement of determining the genome sequences of several strains of this species and comparative genomic analyses. Q fever can be found worldwide, but the epidemiological features of this disease vary according to the geographic area considered, including situations where it is endemic or hyperendemic, and the occurrence of large epidemic outbreaks. In recent years, a major breakthrough in the understanding of the natural history of human infection with C. burnetii was the breaking of the old dichotomy between "acute" and "chronic" Q fever. The clinical presentation of C. burnetii infection depends on both the virulence of the infecting C. burnetii strain and specific risks factors in the infected patient. Moreover, no persistent infection can exist without a focus of infection. This paradigm change should allow better diagnosis and management of primary infection and long-term complications in patients with C. burnetii infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.