ArticleBlood2017
Association among sickle cell trait, fitness, and cardiovascular risk factors in CARDIA.
Article in Blood, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Clinical Outcomes Associated With Sickle Cell Trait: A Systematic Review.Annals of internal medicine · 2018Pooled it
- Venous thromboembolism with contraceptive use in females with sickle cell trait.AJOG global reports · 2025Article
- A Scoping Review on Sex and Gender Differences in the Adverse Health Outcomes of Individuals with Sickle Cell Trait.Women's health reports (New Rochelle, N.Y.) · 2024Article
- The Not-So-Benign Sickle Cell Trait: A Case of Renal Medullary Carcinoma.Journal of community hospital internal medicine perspectives · 2024Article
- Health services use by children identified as heterozygous hemoglobinopathy mutation carriers via newborn screening.BMC pediatrics · 2021Article
- Effects ofJournal of blood medicine · 2020Article
- The carrier state for sickle cell disease is not completely harmless.Haematologica · 2019Review
- Effect of Previous Exposure to Malaria on Blood Pressure in Kilifi, Kenya: A Mendelian Randomization Study.Journal of the American Heart Association · 2019Article
- The current state of sickle cell trait: implications for reproductive and genetic counseling.Hematology. American Society of Hematology. Education Program · 2018Review
- Balancing exercise risk and benefits: lessons learned from sickle cell trait and sickle cell anemia.Hematology. American Society of Hematology. Education Program · 2018Review
- The current state of sickle cell trait: implications for reproductive and genetic counseling.Blood · 2018Review
- Association Between Sickle Cell Trait With Selected Chronic Medical Conditions in U.S. Service Members.Military medicine · 2018Article
- Sickle cell trait knowledge and health literacy in caregivers who receive in-person sickle cell trait education.Molecular genetics & genomic medicine · 2017Article
- Characterization of a mouse model of sickle cell trait: parallels to human trait and a novel finding of cutaneous sensitization.British journal of haematology · 2017Article
- Haematogenous osteoarticular infections in paediatric sickle cell trait patients: A reality in a tertiary centre in West Africa.African journal of paediatric surgery : AJPSArticle
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7 authors at 3 institutions in 1 country.
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Abstract
The contribution of sickle cell trait (SCT) to racial disparities in cardiopulmonary fitness is not known, despite concerns that SCT is associated with exertion-related sudden death. We evaluated the association of SCT status with cross-sectional and longitudinal changes in fitness and risk for hypertension, diabetes, and metabolic syndrome over the course of 25 years among 1995 African Americans (56% women, 18-30 years old) in the Coronary Artery Risk Development in Young Adults (CARDIA) study. Overall, the prevalence of SCT was 6.8% (136/1995) in CARDIA, and over the course of 25 years, 46% (738/1590), 18% (288/1631), and 40% (645/1,611) of all participants developed hypertension, diabetes, and metabolic syndrome, respectively. Compared with participants without SCT, participants with SCT had similar baseline measures of fitness in cross-section, including exercise duration (535 vs 540 seconds;
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.