Evidence map›Paper›PMID 27856369›Full record

ArticleBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2017

Outcomes of Maintenance Therapy with Bortezomib after Autologous Stem Cell Transplantation for Patients with Multiple Myeloma.

Dharshan Sivaraj, Michael M Green, Zhiguo Li, Anthony D Sung, Stefanie Sarantopoulos, Yubin Kang, Gwynn D Long, Mitchell E Horwitz, Richard D Lopez, Keith M Sullivan and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
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  12. Outcome of Multiple Myeloma with Chromosome 1q Gain and 1p Deletion after Autologous Hematopoietic Stem Cell Transplantation: Propensity Score Matched Analysis.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Article
  13. Article
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  15. Pharmacologic agents to prevent and treat relapse after allogeneic hematopoietic cell transplantation.Hematology. American Society of Hematology. Education Program · 2017
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Dharshan SivarajDivision of Cellular Therapy, Duke University, Durham, North Carolina. Electronic address: Dharshan.sivaraj@duke.edu.
Michael M GreenDivision of Cellular Therapy, Duke University, Durham, North Carolina.
Zhiguo LiDepartment of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina.
Anthony D SungDivision of Cellular Therapy, Duke University, Durham, North Carolina.
Stefanie SarantopoulosDivision of Cellular Therapy, Duke University, Durham, North Carolina.
Yubin KangDivision of Cellular Therapy, Duke University, Durham, North Carolina.
Gwynn D LongDivision of Cellular Therapy, Duke University, Durham, North Carolina.
Mitchell E HorwitzDivision of Cellular Therapy, Duke University, Durham, North Carolina.
Richard D LopezDivision of Cellular Therapy, Duke University, Durham, North Carolina.
Keith M SullivanDivision of Cellular Therapy, Duke University, Durham, North Carolina.
David A RizzieriDivision of Cellular Therapy, Duke University, Durham, North Carolina.
Nelson J ChaoDivision of Cellular Therapy, Duke University, Durham, North Carolina.
Cristina GasparettoDivision of Cellular Therapy, Duke University, Durham, North Carolina.
Duke University · US

Funding

Duke CTSA (Composite)KL2TR001115 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, KRAFT, MONICA · 2013 to 2017
$5.1M
NCATS NIH HHS KL2 TR001115
6 · The paper itself

Abstract

Comprehensive recommendations for maintenance therapy after autologous stem cell transplantation (ASCT) for patients with multiple myeloma (MM) have yet to be defined. Bortezomib has been utilized as maintenance therapy after ASCT, but data attesting to the safety and efficacy of this agent compared with lenalidomide in the post-ASCT setting are limited. Therefore, we retrospectively analyzed the outcomes of 102 patients with MM who received maintenance therapy with bortezomib after ASCT at Duke University's adult bone marrow transplant clinic between 2005 and 2015. Maintenance with bortezomib was initiated between 60 and 90 days after ASCT as a single agent 1.3 mg/m

Indexed as

Hematopoietic Stem Cell TransplantationAdultAgedAntineoplastic AgentsBortezomibCombined Modality TherapyDisease-Free SurvivalDrug EvaluationFemaleHumansIn Situ Hybridization, FluorescenceKaplan-Meier EstimateLenalidomideMaintenance ChemotherapyMaleMiddle AgedAntineoplastic AgentsBortezomibLenalidomideProteasome InhibitorsThalidomideAutologous stem cell transplantationBortezomibMaintenance therapyMultiple myeloma

Identifiers

PMID27856369
PMCPMC11099879
OpenAlexW2549271193

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.