ReviewNeurotoxicology and teratology
Anesthetic neurotoxicity: Apoptosis and autophagic cell death mediated by calcium dysregulation.
Review in Neurotoxicology and teratology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 44 citations in OpenAlex.
- Effects of Sevoflurane on the Development of a Human Brain Microphysiological System.International journal of molecular sciences · 2026Article
- Sevoflurane induces developmental cardiotoxicity via AMPKα2 dysregulation in zebrafish.Cell & bioscience · 2026Article
- Non-anesthetic Effects of Anesthetics and Organ Protection.Current neuropharmacology · 2026Review
- From neurotoxicity to neuroprotection: Rethinking GABACell biology and toxicology · 2025Review
- Neuroprotective effect of erythropoietin on anesthesia-induced neurotoxicity through the modulation of autophagy in Caenorhabditis elegans.Korean journal of anesthesiology · 2024Article
- Xenobiotics Triggering Acute Intermittent Porphyria and Their Effect on Mouse Brain Respiratory Complexes.Journal of xenobiotics · 2024Article
- Editorial: Anesthetic-induced neurotoxicity and neurocognitive impairment of vulnerable brains.Frontiers in aging neuroscience · 2023Article
- Anesthesia, the developing brain, and dexmedetomidine for neuroprotection.Frontiers in neurology · 2023Review
- Article
- Effect of preconditioning on propofol-induced neurotoxicity during the developmental period.PloS one · 2022Article
- Low Intensity Electromagnetic Fields Act via Voltage-Gated Calcium Channel (VGCC) Activation to Cause Very Early Onset Alzheimer's Disease: 18 Distinct Types of Evidence.Current Alzheimer research · 2022Article
- Apoptosis inhibition is involved in improvement of sevoflurane-induced cognitive impairment following normobaric hyperoxia preconditioning in aged rats.Experimental and therapeutic medicine · 2021Article
- A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death, perturbation of growth and synaptic assembly.Scientific reports · 2021Article
- The differential effects of isoflurane and sevoflurane on neonatal mice.Scientific reports · 2020Article
- Baicalin Suppresses Bilirubin-Induced Apoptosis and Inflammation by Regulating p38 Mitogen-Activated Protein Kinases (MAPK) Signaling in Neonatal Neurons.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Dantrolene Ameliorates Impaired Neurogenesis and Synaptogenesis in Induced Pluripotent Stem Cell Lines Derived from Patients with Alzheimer's Disease.Anesthesiology · 2020Article
- Article
- Alzheimer's Disease Presenilin-1 Mutation Sensitizes Neurons to Impaired Autophagy Flux and Propofol Neurotoxicity: Role of Calcium Dysregulation.Journal of Alzheimer's disease : JAD · 2019Article
- Article
- Neurotoxicity of Anesthesia in Children: Prevention and Treatment.Current treatment options in neurology · 2018Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
A number of findings suggested that general anesthetics induced neural cell death by apoptosis in various animal models. Although clinical evidence regarding the correlation between anesthetic exposures at young age and subsequent cognitive impairments remains unclear, repeated or consistent exposures to general anesthetics may be a potential harmful risk in developing human brains. The mechanisms underlying the anesthetic neurotoxicity have received extensive attention recently. We will attempt a brief review to summarize current understanding on the role of both apoptosis and autophagic cell death mediated by calcium dysregulation in anesthetic neurotoxicity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.