Evidence map›Paper›PMID 27855779›Full record

ArticleeLife2016

Local chromosome context is a major determinant of crossover pathway biochemistry during budding yeast meiosis.

Darpan Medhi, Alastair Sh Goldman, Michael Lichten

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Diffusion and distal linkages govern interchromosomal dynamics during meiotic prophase.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Rewiring Meiosis for Crop Improvement.Frontiers in plant science · 2021
    Review
  14. Meiotic Crossover Patterning.Frontiers in cell and developmental biology · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Darpan MedhiLaboratory of Biochemistry and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, United States.
Alastair Sh GoldmanSheffield Institute for Nucleic Acids, The University of Sheffield, Sheffield, United Kingdom.
Michael LichtenLaboratory of Biochemistry and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, United States.ORCID 0000-0001-9707-2956
National Cancer Institute · USUniversity of Sheffield · GB

Funding

Mechanism of Meiotic RecombinationZIABC005268 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LICHTEN, MICHAEL J · 2009 to 2023
$17.3M
6 · The paper itself

Abstract

The budding yeast genome contains regions where meiotic recombination initiates more frequently than in others. This pattern parallels enrichment for the meiotic chromosome axis proteins Hop1 and Red1. These proteins are important for Spo11-catalyzed double strand break formation; their contribution to crossover recombination remains undefined. Using the sequence-specific

Indexed as

Crossing Over, GeneticMeiosisChromosomes, FungalSaccharomyces cerevisiae ProteinsSaccharomycetalesSaccharomyces cerevisiae Proteinschromosomeschromosome structuregenesHolliday junction resolvasehomologous recombination mechanismsmeiotic chromosome axisS. cerevisiaeVMA1-derived endonuclease

Identifiers

PMID27855779
PMCPMC5222560
OpenAlexW2481326716

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.