Evidence map›Paper›PMID 27855091›Full record

ArticleBMJ open2016

Healthcare costs in chronic kidney disease and renal replacement therapy: a population-based cohort study in Sweden.

Jonas K Eriksson, Martin Neovius, Stefan H Jacobson, Carl-Gustaf Elinder, Britta Hylander

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Financial Toxicity and Kidney Disease in Children and Adults: A Scoping Review.International journal of nephrology and renovascular disease · 2025
    Review
  6. Article
  7. Data-Driven Evidence-Based Patient-Centered Optimal Initiation Time for Dialysis Treatment.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Kidney outcomes with finerenone: an analysis from the FIGARO-DKD study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
  18. Review
  19. Article
  20. The Growing Challenge of Chronic Kidney Disease: An Overview of Current Knowledge.International journal of nephrology · 2023 · on this map
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jonas K ErikssonClinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Martin NeoviusClinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Stefan H JacobsonDivision of Nephrology, Department of Clinical Sciences, Danderyd University Hospital, Stockholm, Sweden.
Carl-Gustaf ElinderNephrology Unit, Department of Clinical Sciences, Intervention and Technology, Stockholm, Sweden.
Britta HylanderUnit of Renal Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SEDanderyds sjukhus · SEStockholm County Council · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare healthcare costs in chronic kidney disease (CKD) stage 4 or 5 not on dialysis (estimated glomerular filtration rate <30 mL/min/1.73m

designPopulation-based cohort study.

settingSwedish national healthcare system.

participantsPrevalent adult patients with CKD 4 or 5 (n=1046, mean age 68 years), on peritoneal dialysis (n=101; 64 years), on haemodialysis (n=460; 65 years) and with renal transplants (n=825; 52 years) were identified in Stockholm County clinical quality registers for renal disease on 1 January 2010. 5 general population comparators from the same county were matched to each patient by age, sex and index year. PRIMARY AND SECONDARY OUTCOME MEASURES: Annual healthcare costs in 2009 incurred through inpatient and hospital-based outpatient care and dispensed prescription drugs ascertained from nationwide healthcare registers. Secondary outcomes were annual number of hospital days and outpatient care visits.

resultsPatients on haemodialysis had the highest mean annual cost (€87 600), which was 1.49 (95% CI 1.38 to 1.60) times that observed in peritoneal dialysis (€58 600). The mean annual cost was considerably lower in transplanted patients (€15 500) and in the CKD group (€9600). In patients on haemodialysis, outpatient care costs made up more than two-thirds (€62 500) of the total, while costs related to fluids ($29 900) was the largest cost component in patients on peritoneal dialysis (51%). Compared with their matched general population comparators, the mean annual cost (95% CI) in patients on haemodialysis, peritoneal dialysis, transplanted patients and patients with CKD was 45 (39 to 51), 29 (22 to 37), 11 (10 to 13) and 4.0 (3.6 to 4.5) times higher, respectively.

conclusionsThe mean annual costs were ∼50% higher in patients on haemodialysis than in those on peritoneal dialysis. Compared with the general population, costs were substantially elevated in all groups, from 4-fold in patients with CKD to 11, 29 and 45 times higher in transplanted patients and patients on peritoneal dialysis and haemodialysis, respectively.

Indexed as

Health Care CostsAdultAgedAmbulatory CareCohort StudiesFemaleGlomerular Filtration RateHospitalizationHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedNational Health ProgramsPeritoneal DialysisRegistriesHEALTH ECONOMICS

Identifiers

PMID27855091
PMCPMC5073563
OpenAlexW2529417562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.