Evidence map›Paper›PMID 27855079›Full record

ArticleAntimicrobial agents and chemotherapy2017

Chromosomal Amplification of the blaOXA-58 Carbapenemase Gene in a Proteus mirabilis Clinical Isolate.

Delphine Girlich, Rémy A Bonnin, Pierre Bogaerts, Morgane De Laveleye, Daniel T Huang, Laurent Dortet, Philippe Glaser, Youri Glupczynski, Thierry Naas

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Adaptation and performance evaluation of the French society of microbiology algorithm for detection of carbapenemase-producing enterobacterales using VITEK2 antibiotic susceptibility testing system.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Clinical microbiology reviews · 2025
    Review
  4. Article
  5. Impact of COVID-19 pandemic on antimicrobial resistance of Proteus mirabilis in a Brazilian hospital.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. High Prevalence of OXA-23 Carbapenemase-ProducingAntimicrobial agents and chemotherapy · 2022
    Article
  10. Diversity of carbapenem-resistantMicrobial genomics · 2022
    Article
  11. Article
  12. Outbreak of OXA-48-producing Enterobacterales in a haematological ward associated with an uncommon environmental reservoir, France, 2016 to 2019.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Functional Analysis of theAntibiotics (Basel, Switzerland) · 2020
    Article
  17. Article
  18. Article
  19. Review
  20. First Occurrence of the OXA-198 Carbapenemase inAntimicrobial agents and chemotherapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Delphine GirlichEA7361, Université Paris-Sud, Université Paris-Saclay, LabEx Lermit, Bacteriology-Hygiene Unit, APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Rémy A BonninEA7361, Université Paris-Sud, Université Paris-Saclay, LabEx Lermit, Bacteriology-Hygiene Unit, APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.ORCID 0000-0002-2307-3232
Pierre BogaertsBelgian National Reference Laboratory for Monitoring of Antimicrobial Resistance in Gram-Negative Bacteria, Yvoir, Belgium.
Morgane De LaveleyeCHU UCL Namur, Yvoir, Belgium.
Daniel T HuangBelgian National Reference Laboratory for Monitoring of Antimicrobial Resistance in Gram-Negative Bacteria, Yvoir, Belgium.
Laurent DortetEA7361, Université Paris-Sud, Université Paris-Saclay, LabEx Lermit, Bacteriology-Hygiene Unit, APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.ORCID 0000-0001-6596-7384
Philippe GlaserEcology and Evolution of Resistance to Antibiotics Unit, Institut Pasteur-APHP-Université Paris Sud, Paris, France pglaser@pasteur.fr thierry.naas@bct.aphp.fr.
Youri GlupczynskiBelgian National Reference Laboratory for Monitoring of Antimicrobial Resistance in Gram-Negative Bacteria, Yvoir, Belgium.
Thierry NaasEA7361, Université Paris-Sud, Université Paris-Saclay, LabEx Lermit, Bacteriology-Hygiene Unit, APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France pglaser@pasteur.fr thierry.naas@bct.aphp.fr.
Université Paris-Sud · FRCHU Dinant Godinne UCL Namur · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Horizontal gene transfer may occur between distantly related bacteria, thus leading to genetic plasticity and in some cases to acquisition of novel resistance traits. Proteus mirabilis is an enterobacterial species responsible for human infections that may express various acquired β-lactam resistance genes, including different classes of carbapenemase genes. Here we report a Proteus mirabilis clinical isolate (strain 1091) displaying resistance to penicillin, including temocillin, together with reduced susceptibility to carbapenems and susceptibility to expanded-spectrum cephalosporins. Using biochemical tests, significant carbapenem hydrolysis was detected in P. mirabilis 1091. Since PCR failed to detect acquired carbapenemase genes commonly found in Enterobacteriaceae, we used a whole-genome sequencing approach that revealed the presence of bla

Indexed as

AdultBacterial Proteinsbeta-LactamasesBinding SitesChromosomes, BacterialDrug Resistance, BacterialEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialHumansIntegrasesMaleMicrobial Sensitivity TestsMultigene FamilyProphagesProteus InfectionsBacterial Proteinsbeta-LactamasescarbapenemaseEscherichia coli ProteinsIntegrasesXerC protein, E coliXerD protein, E coliAcinetobacter baumanniibacteriophagecarbapenemsOXA-58Proteus mirabilisXerC-XerD recombinase

Identifiers

PMID27855079
PMCPMC5278702
OpenAlexW2557114865

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.