ArticleeLife2016
Rotating waves during human sleep spindles organize global patterns of activity that repeat precisely through the night.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
114 citing papers in PubMed, 1 synthesis or guideline pooled it, 230 citations in OpenAlex.
- Pooled it
- Article
- Article
- Article
- Random auditory stimulation during sleep disturbs traveling slow waves and declarative memory.iScience · 2026Article
- Enhanced Taylor-Aris dispersion in slender pulsatile annular channels: Implications for perivascular solute transport.Journal of fluid mechanics · 2026Article
- Hidden Spirals Reveal the Neurocomputational Mechanisms of Traveling Waves in Human Memory.bioRxiv : the preprint server for biology · 2026Article
- Dynamical mechanisms for coordinating long-term working memory based on the precision of spike-timing in cortical neurons.Biological cybernetics · 2026Review
- Propofol-induced loss of responsiveness reorganizes cortical traveling waves in the human brain.bioRxiv : the preprint server for biology · 2026Article
- Planar, spiral, and concentric traveling waves distinguish behavioral states in human memory.Nature communications · 2026Article
- A Spatiotemporal Perspective on Dynamical Computation in Neural Information Processing Systems.ArXiv · 2026Article
- A proposal for realizing cognitive functions using traveling waves, phase-locked and synchronized patterns, holography, neural mixing, and single sideband communications.Frontiers in computational neuroscience · 2026Article
- Quantifying cortex-wide traveling brain waves of complex patterns with a graph-based algorithm.Frontiers in computational neuroscience · 2026Article
- Wave turbulence and cortical dynamics.Frontiers in computational neuroscience · 2026Article
- Task-invariant anterior-to-posterior large-scale phase gradients of electrocorticogram oscillations during picture naming and wrist extension.Communications biology · 2025Article
- Attention-induced perceptual traveling waves in binocular rivalry.Journal of vision · 2025Article
- A Scalable Fishbone Nanowire Array (FINE) for 3D Quasi-Intracellular Recording in Intact Brains.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Network Desynchronization with Sine Waves: from Synchrony to Asynchrony by Periodic Stimulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Spatiotemporal dynamics of sleep spindles form spiral waves that predict overnight memory consolidation and age-related memory decline.Communications biology · 2025Article
- Interictal network dysfunction and cognitive impairment in epilepsy.Nature reviews. Neuroscience · 2025Review
54 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
During sleep, the thalamus generates a characteristic pattern of transient, 11-15 Hz sleep spindle oscillations, which synchronize the cortex through large-scale thalamocortical loops. Spindles have been increasingly demonstrated to be critical for sleep-dependent consolidation of memory, but the specific neural mechanism for this process remains unclear. We show here that cortical spindles are spatiotemporally organized into circular wave-like patterns, organizing neuronal activity over tens of milliseconds, within the timescale for storing memories in large-scale networks across the cortex via spike-time dependent plasticity. These circular patterns repeat over hours of sleep with millisecond temporal precision, allowing reinforcement of the activity patterns through hundreds of reverberations. These results provide a novel mechanistic account for how global sleep oscillations and synaptic plasticity could strengthen networks distributed across the cortex to store coherent and integrated memories.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.