Evidence map›Paper›PMID 27854526›Full record

ArticleAmerican journal of public health2017

Evaluating Public Health Interventions: 5. Causal Inference in Public Health Research-Do Sex, Race, and Biological Factors Cause Health Outcomes?

M Maria Glymour, Donna Spiegelman

Abstract read
In one paragraph

Article in American journal of public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Causal Inference in Health Disparities Research.Annual review of public health · 2026
    Review
  5. Article
  6. Racism Counterfactuals in Health Research.Journal of racial and ethnic health disparities · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

M Maria GlymourM. Maria Glymour is with the Department of Epidemiology and Biostatistics, University of California, San Francisco. Donna Spiegelman is with the Departments of Epidemiology, Biostatistics, Nutrition, and Global Health, Harvard T. H. Chan School of Public Health, Boston, MA.
Donna SpiegelmanM. Maria Glymour is with the Department of Epidemiology and Biostatistics, University of California, San Francisco. Donna Spiegelman is with the Departments of Epidemiology, Biostatistics, Nutrition, and Global Health, Harvard T. H. Chan School of Public Health, Boston, MA.

Funding

Comprehensive Translational Science Analytics Tools for the Global Health AgendaDP1ES025459 · NIEHS · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2018
$4.1M
New Methods for the design and evaluation of large HIV prevention interventionsR01AI112339 · NIAID · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2017
$2.7M
NIAID NIH HHS R01 AI112339NIEHS NIH HHS DP1 ES025459
6 · The paper itself

Abstract

Counterfactual frameworks and statistical methods for supporting causal inference are powerful tools to clarify scientific questions and guide analyses in public health research. Counterfactual accounts of causation contrast what would happen to a population's health under alternative exposure scenarios. A long-standing debate in counterfactual theory relates to whether sex, race, and biological characteristics, including obesity, should be evaluated as causes, given that these variables do not directly correspond to clearly defined interventions. We argue that sex, race, and biological characteristics are important health determinants. Quantifying the overall health effects of these variables is often a natural starting point for disparities research. Subsequent assessments of biological or social pathways mediating those effects can facilitate the development of interventions designed to reduce disparities.

Indexed as

Biological FactorsCausalityEthnicityPublic HealthResearch DesignSex FactorsConfounding Factors, EpidemiologicFemaleHealth Services ResearchHumansMaleModels, StatisticalPrejudiceBiological Factors

Identifiers

PMID27854526
PMCPMC5308179

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.