Evidence map›Paper›PMID 27854320›Full record

ArticleDiagnostics (Basel, Switzerland)2016

The Effect of Exercise on Salivary Viscosity.

Antoon J M Ligtenberg, Erwin H S Liem, Henk S Brand, Enno C I Veerman

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
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  3. Article
  4. Oral Health Status in Moroccan Hemodialysis Patients.Clinical, cosmetic and investigational dentistry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Antoon J M LigtenbergDepartment of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, 1081LA, Amsterdam, The Netherlands. a.ligtenberg@acta.nl.
Erwin H S LiemDepartment of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, 1081LA, Amsterdam, The Netherlands. Erwinliem@hotmail.com.
Henk S BrandDepartment of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, 1081LA, Amsterdam, The Netherlands. h.brand@acta.nl.
Enno C I VeermanDepartment of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, 1081LA, Amsterdam, The Netherlands. e.veerman@acta.nl.
Academic Center for Dentistry Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A common experience after exercise is the presence of a thick and sticky saliva layer on the oral surfaces, which causes a feeling of a dry mouth. Since the salivary mucin MUC5B is responsible for the visco-elastic behavior of saliva, in the present study we explored the effect of exercise on both the salivary viscosity and the secretion of MUC5B in saliva. Twenty healthy dental students performed an aerobic exercise by cycling for 15 min on cycle-ergometers at a heart rate of 130-140 beats per minute. Saliva was collected at three time points: before exercise, immediately after exercise and after 30 min recovery. Salivary flow rate, viscosity, amylase activity, total protein, carbohydrate and MUC5B concentration were determined. Salivary flow rate, protein and amylase did not change significantly. Immediately after exercise, the salivary viscosity and carbohydrate concentration were significantly higher than at baseline and after 30 min recovery. Immediately after exercise, the MUC5B concentration was significantly higher than after 30 min recovery. It is concluded that the presence of thick saliva after exercise is at least partially due to an increased secretion of MUC5B.

Indexed as

amylaseexerciseMUC5Bprotein

Identifiers

PMID27854320
PMCPMC5192515
OpenAlexW2555025305

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.