Evidence map›Paper›PMID 27854316›Full record

ReviewNutrients2016

Causes, Consequences and Public Health Implications of Low B-Vitamin Status in Ageing.

Kirsty Porter, Leane Hoey, Catherine F Hughes, Mary Ward, Helene McNulty

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 3 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 3 syntheses or guidelines pooled it, 147 citations in OpenAlex.

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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kirsty PorterNorthern Ireland Centre for Food and Health, Ulster University, Cromore Road, Coleraine BT52 1SA, UK. porter-k7@email.ulster.ac.uk.
Leane HoeyNorthern Ireland Centre for Food and Health, Ulster University, Cromore Road, Coleraine BT52 1SA, UK. l.hoey@ulster.ac.uk.
Catherine F HughesNorthern Ireland Centre for Food and Health, Ulster University, Cromore Road, Coleraine BT52 1SA, UK. c.hughes@ulster.ac.uk.
Mary WardNorthern Ireland Centre for Food and Health, Ulster University, Cromore Road, Coleraine BT52 1SA, UK. mw.ward@ulster.ac.uk.
Helene McNultyNorthern Ireland Centre for Food and Health, Ulster University, Cromore Road, Coleraine BT52 1SA, UK. h.mcnulty@ulster.ac.uk.
University of Ulster · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The potential protective roles of folate and the metabolically related B-vitamins (vitamins B12, B6 and riboflavin) in diseases of ageing are of increasing research interest. The most common cause of folate and riboflavin deficiencies in older people is low dietary intake, whereas low B12 status is primarily associated with food-bound malabsorption, while sub-optimal vitamin B6 status is attributed to increased requirements in ageing. Observational evidence links low status of folate and the related B-vitamins (and/or elevated concentrations of homocysteine) with a higher risk of degenerative diseases including cardiovascular disease (CVD), cognitive dysfunction and osteoporosis. Deficient or low status of these B-vitamins alone or in combination with genetic polymorphisms, including the common

Indexed as

AgingNutritional StatusVitamin B DeficiencyDietDietary SupplementsHumansVitamin B ComplexVitamin B ComplexageingB-vitaminscardiovascular diseasecognitive dysfunctiondegenerative diseasesdementiamethylenetetrahydrofolate reductase (MTHFR)osteoporosis

Identifiers

PMID27854316
PMCPMC5133110
OpenAlexW2549839667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.