Evidence map›Paper›PMID 27854313›Full record

SynthesisInternational journal of environmental research and public health2016

Association between the Angiotensin-Converting Enzyme (ACE) Genetic Polymorphism and Diabetic Retinopathy-A Meta-Analysis Comprising 10,168 Subjects.

Shasha Luo, Chao Shi, Furu Wang, Zhifeng Wu

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. The Role of SGLT2 Inhibitor on the Treatment of Diabetic Retinopathy.Journal of diabetes research · 2020 · on this map
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Shasha LuoDepartment of Ophthalmology, Nanjing Medical University Affiliated Wuxi Second Hospital, 68 Zhongshan Road, Wuxi 214002, China. luoshasha403@163.com.
Chao ShiWuxi Center for Disease Control and Prevention, 499 Jincheng Road, Wuxi 214023, China. shichao.xo@163.com.
Furu WangJiangsu Provincial Center for Disease Prevention and Control, 172 Jiangsu Road, Nanjing 210029, China. furuwang83@163.com.
Zhifeng WuDepartment of Ophthalmology, Nanjing Medical University Affiliated Wuxi Second Hospital, 68 Zhongshan Road, Wuxi 214002, China. zhifengwu2013@126.com.
Jiangsu Provincial Center for Disease Control and Prevention · CNSecond Hospital of Shanxi Medical University · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims-to address the inconclusive findings of the association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism on risk of diabetic retinopathy (DR), a meta-analysis was conducted. Methods-we conducted a meta-analysis on 4252 DR cases and 5916 controls from 40 published studies by searching electronic databases and reference lists of relevant articles. A random-effects or fixed-effects model was used to estimate the overall and stratification effect sizes on

Indexed as

Genetic Predisposition to DiseaseAdultAgedAged, 80 and overAsian PeopleDiabetes Mellitus, Type 2Diabetic RetinopathyFemaleGenome-Wide Association StudyHumansMaleMiddle AgedPeptidyl-Dipeptidase APolymorphism, GeneticProspective StudiesRisk AssessmentACE protein, humanPeptidyl-Dipeptidase AACE I/Ddiabetic retinopathyDM typeethnicitypolymorphism

Identifiers

PMID27854313
PMCPMC5129352
OpenAlexW2556346122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.