Evidence map›Paper›PMID 27854048›Full record

ArticleBioMedicine2016

Magnesium deficiency and oxidative stress: an update.

Anastasia A Zheltova, Maria V Kharitonova, Igor N Iezhitsa, Alexander A Spasov

Open access · diamondAbstract read
In one paragraph

Article in BioMedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 1 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 1 synthesis or guideline pooled it, 216 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Association of the Modified Endothelial Activation and Stress Index with MASLD and Liver Fibrosis: Effect Modification by Magnesium Intake.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Beyond magnesium sulphate - Rethinking magnesium's impact on maternal and foetal health in low to middle-income countries: A scoping review.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Anastasia A ZheltovaDepartment of Pharmacology, Volgograd State Medical University, Pl. Pavshikh Bortsov, 1, Volgograd, 400131, Russia.
Maria V KharitonovaDepartment of Pharmacology, Volgograd State Medical University, Pl. Pavshikh Bortsov, 1, Volgograd, 400131, Russia.
Igor N IezhitsaDepartment of Pharmacology, Volgograd State Medical University, Pl. Pavshikh Bortsov, 1, Volgograd, 400131, Russia. iezhitsa@salam.uitm.edu.my.
Alexander A SpasovDepartment of Pharmacology, Volgograd State Medical University, Pl. Pavshikh Bortsov, 1, Volgograd, 400131, Russia.
Hospital Sungai Buloh · MYUniversität Innsbruck · ATVolgograd State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnesium deficiency (MgD) has been shown to impact numerous biological processes at the cellular and molecular levels. In the present review, we discuss the relationship between MgD and oxidative stress (OS). MgD is accompanied by increased levels of OS markers such as lipid, protein and DNA oxidative modification products. Additionally, a relationship was detected between MgD and a weakened antioxidant defence. Different mechanisms associated with MgD are involved in the development and maintenance of OS. These mechanisms include systemic reactions such as inflammation and endothelial dysfunction, as well as changes at the cellular level, such as mitochondrial dysfunction and excessive fatty acid production.

Indexed as

AntioxidantsLipid peroxidationMagnesiumMagnesium deficiencyOxidative stressReactive oxygen species

Identifiers

PMID27854048
PMCPMC5112180
OpenAlexW2551474197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.