Evidence map›Paper›PMID 27853992›Full record

ReviewVirologica Sinica2017

Progress towards understanding the pathogenesis of dengue hemorrhagic fever.

Xiaojing Pang, Rudian Zhang, Gong Cheng

Abstract readReview
In one paragraph

Review in Virologica Sinica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Recommendations for dengue vaccine implementation in the elderly population.Therapeutic advances in vaccines and immunotherapy · 2025
    Review
  13. Article
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  15. Kaempferol: A Review of Current Evidence of Its Antiviral Potential.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaojing PangTsinghua-Peking Center for Life Sciences, School of Medicine, Tsinghua University, Beijing, 100084, China.
Rudian ZhangTsinghua-Peking Center for Life Sciences, School of Medicine, Tsinghua University, Beijing, 100084, China.
Gong ChengTsinghua-Peking Center for Life Sciences, School of Medicine, Tsinghua University, Beijing, 100084, China. gongcheng@mail.tsinghua.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue virus (DENV) is a mosquito-borne virus belonging to the Flaviviridae family. There are 4 serotypes of DENV that cause human disease through transmission by mosquito vectors. DENV infection results in a broad spectrum of clinical symptoms, ranging from mild fever to dengue hemorrhagic fever (DHF), the latter of which can progress to dengue shock syndrome (DSS) and death. Researchers have made unremitting efforts over the last half-century to understand DHF pathogenesis. DHF is probably caused by multiple factors, such as virus-specific antibodies, viral antigens and host immune responses. This review summarizes the current progress of studies on DHF pathogenesis, which may provide important information for achieving effective control of dengue in the future.

Indexed as

Host-Pathogen InteractionsAntibodies, BlockingAntibodies, ViralDengue VirusHumansSevere DengueAntibodies, BlockingAntibodies, Viralantibody-dependent enhancement (ADE)dengue hemorrhagic fever (DHF)DENVgenomeNS1T cell

Identifiers

PMID27853992
PMCPMC6702245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.