Evidence map›Paper›PMID 27853883›Full record

ArticleWiener klinische Wochenschrift2016

Nutritional status and its effects on muscle wasting in patients with chronic heart failure: insights from Studies Investigating Co-morbidities Aggravating Heart Failure.

Masakazu Saitoh, Marcelo Rodrigues Dos Santos, Nicole Ebner, Amir Emami, Masaaki Konishi, Junichi Ishida, Miroslava Valentova, Anja Sandek, Wolfram Doehner, Stefan D Anker and 1 more

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In one paragraph

Article in Wiener klinische Wochenschrift, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 7 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 7 syntheses or guidelines pooled it, 61 citations in OpenAlex.

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  16. The Role of Sarcopenia in Heart Failure with Depression.Reviews in cardiovascular medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Masakazu SaitohInnovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 40, Göttingen, 37099, Germany. msaitoh@shi.heart.or.jp.
Marcelo Rodrigues Dos SantosInnovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 40, Göttingen, 37099, Germany.
Nicole EbnerInnovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 40, Göttingen, 37099, Germany.
Amir EmamiInnovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 40, Göttingen, 37099, Germany.
Masaaki KonishiInnovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 40, Göttingen, 37099, Germany.
Junichi IshidaInnovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 40, Göttingen, 37099, Germany.
Miroslava ValentovaInnovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 40, Göttingen, 37099, Germany.
Anja SandekInnovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 40, Göttingen, 37099, Germany.
Wolfram DoehnerCenter for Stroke Research Berlin, and Department of Cardiology, Virchow Klinikum, Charité-Universitätsmedizin, Berlin, Germany.
Stefan D AnkerInnovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 40, Göttingen, 37099, Germany.
Stephan von HaehlingInnovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen, Robert-Koch-Straße 40, Göttingen, 37099, Germany.
University of Göttingen · DEUniversitätsmedizin Göttingen · DECharité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInadequate nutritional status has been linked to poor outcomes in patients with heart failure (HF). Skeletal muscle wasting affects about 20% of ambulatory patients with HF. The impact of nutritional intake and appetite on skeletal muscle wasting has not been investigated so far. We sought to investigate the impact of nutritional status on muscle wasting and mortality in ambulatory patients with HF.

methodsWe studied 130 ambulatory patients with HF who were recruited as a part of the Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF) program. Muscle wasting was defined according to criteria of sarcopenia, i.e., appendicular skeletal muscle mass two standard deviations below the mean of a healthy reference group aged 18-40 years. Nutritional status was evaluated using the Mini-Nutritional Assessment-Short Form (MNA-SF). Functional capacity was assessed as peak oxygen consumption (peak VO

resultsAt baseline, 19 patients (15%) presented with muscle wasting. Patients with muscle wasting had significantly lower values of peak VO

conclusionMNA-SF is an independent predictor of muscle wasting and mortality in ambulatory patients with HF. Nutritional screening should be included as a fundamental part of the overall assessment of these patients.

Indexed as

Nutritional StatusAdolescentAdultAgedAge DistributionCachexiaCausalityChronic DiseaseComorbidityFemaleGermanyHumansMaleMalnutritionPhysical FitnessRisk FactorsHeart failureMalnutritionMini-nutritional assessmentMortalityMuscle wasting

Identifiers

PMID27853883
OpenAlexW2554504340

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.