Evidence map›Paper›PMID 27853732›Full record

ReviewFrontiers in cell and developmental biology2016

Inflammation Shapes Stem Cells and Stemness during Infection and Beyond.

Stella Michael, Charis Achilleos, Theofano Panayiotou, Katerina Strati

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  5. Retina regeneration: lessons from vertebrates.Oxford open neuroscience · 2022
    Review
  6. Low Molecular Weight Sericin Enhances theFrontiers in bioengineering and biotechnology · 2022
    Article
  7. Article
  8. Article
  9. Review
  10. Review
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  12. Article
  13. Review
  14. Article
  15. Treg regulation of the epithelial stem cell lineage.Journal of immunology and regenerative medicine · 2020
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Immunological modulation following bone marrow-derived mesenchymal stromal cells and Th17 lymphocyte co-cultures.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Stella MichaelDepartment of Biological Sciences, University of Cyprus Nicosia, Cyprus.
Charis AchilleosDepartment of Biological Sciences, University of Cyprus Nicosia, Cyprus.
Theofano PanayiotouDepartment of Biological Sciences, University of Cyprus Nicosia, Cyprus.
Katerina StratiDepartment of Biological Sciences, University of Cyprus Nicosia, Cyprus.
University of Cyprus · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outcome of an inflammatory incident can hang in the balance between restoring health and tissue integrity on the one hand, and promoting aberrant tissue homeostasis and adverse outcomes on the other. Both microbial-related and sterile inflammation is a complex response characterized by a range of innate immune cell types, which produce and respond to cytokine mediators and other inflammatory signals. In turn, cells native to the tissue in question can sense these mediators and respond by migrating, proliferating and regenerating the tissue. In this review we will discuss how the specific outcomes of inflammatory incidents are affected by the direct regulation of stem cells and cellular plasticity. While less well appreciated than the effects of inflammatory signals on immune cells and other differentiated cells, the effects are crucial in understanding inflammation and appropriately managing therapeutic interventions.

Indexed as

inflammationstem cellsstem cells and microbesstem cells and sterile inflammationstemness

Identifiers

PMID27853732
PMCPMC5089974
OpenAlexW2546461049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.