Evidence map›Paper›PMID 27853655›Full record

ArticleAutism-open access2016

A Killer Immunoglobulin - Like Receptor Gene - Content Haplotype and A Cognate Human Leukocyte Antigen Ligand are Associated with Autism.

Anthony Torres, Jonna Westover, Michael Benson, Randall Johnson, Annelise Dykes

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Autism-open access, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. THE EXPOSOME IN HUMAN EVOLUTION: FROM DUST TO DIESEL.The Quarterly review of biology · 2019
    Article
  2. Neuroinflammation in Autism Spectrum Disorders: Role of High Mobility Group Box 1 Protein.International journal of molecular and cellular medicine · 2017
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anthony TorresCenter for Persons with Disabilities, Utah State University, Logan, Utah, USA.
Jonna WestoverCenter for Persons with Disabilities, Utah State University, Logan, Utah, USA.
Michael BensonCenter for Persons with Disabilities, Utah State University, Logan, Utah, USA.
Randall JohnsonCenter for Persons with Disabilities, Utah State University, Logan, Utah, USA.
Annelise DykesCenter for Persons with Disabilities, Utah State University, Logan, Utah, USA.
Utah State University · US

Funding

CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

The killing activity of natural killer cells is largely regulated by the binding of class I human leukocyte antigen cognate ligands to killer cell immunoglobulin - like receptor proteins. The killer cell immunoglobulin - like receptor gene - complex contains genes that activate and others that inhibit the killing state of natural killer cells depending on the binding of specific human leukocyte antigen cognate ligands. It has been suggested in previous publications that activating human leukocyte antigen/killer - cell immunoglobulin - like receptor complexes are increased in people with autism. We present data, which suggests that an activating cB01/tA01 killer cell immunoglobulin - like receptor gene - content haplotype and the cognate ligand human leukocyte antigen - C1

Indexed as

AutismHuman leukocyte antigen (HLA) allelesKiller - cell immunoglobulin - like receptors (KIR)KIR geneTransmission disequilibrium test (TDT)

Identifiers

PMID27853655
PMCPMC5108574
OpenAlexW2407470024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.