Evidence map›Paper›PMID 27853645›Full record

ArticleOncoimmunology

Promoter methylation of the immune checkpoint receptor

Diane Goltz, Heidrun Gevensleben, Jörn Dietrich, Jörg Ellinger, Jennifer Landsberg, Glen Kristiansen, Dimo Dietrich

Abstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Trial
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  11. The roles of PD-1/PD-L1 in the prognosis and immunotherapy of prostate cancer.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Review
  12. Understanding LAG-3 Signaling.International journal of molecular sciences · 2021
    Review
  13. Deciphering DNA Methylation in HIV Infection.Frontiers in immunology · 2021
    Review
  14. Review
  15. Article
  16. Review
  17. The landscape ofEpigenetics · 2020
    Article
  18. Article
  19. Article
  20. Journal for immunotherapy of cancer · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Diane GoltzInstitute of Pathology, University Hospital Bonn , Bonn, Germany.
Heidrun GevenslebenInstitute of Pathology, University Hospital Bonn , Bonn, Germany.
Jörn DietrichDepartment of Otolaryngology, Head and Neck Surgery, University Hospital Bonn , Bonn, Germany.
Jörg EllingerDepartment of Urology, University Hospital Bonn , Bonn, Germany.
Jennifer LandsbergDepartment of Dermatology, University Hospital Bonn , Bonn, Germany.
Glen KristiansenInstitute of Pathology, University Hospital Bonn , Bonn, Germany.
Dimo DietrichInstitute of Pathology, University Hospital Bonn, Bonn, Germany; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biomarkers that facilitate the prediction of disease recurrence in prostate cancer (PCa) may enable physicians to personalize treatment for individual patients. In the current study,

Indexed as

DNA methylationPD-1PDCD1prognostic biomarkerprostate cancer

Identifiers

PMID27853645
PMCPMC5087295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.