ArticleIranian journal of radiology : a quarterly journal published by the Iranian Radiological Society2016
Changes of T2 Relaxation Time From Neoadjuvant Chemotherapy in Breast Cancer Lesions.
Article in Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Applications of TFrontiers in oncology · 2022Pooled it
- A Comparison of 7 Tesla MR Spectroscopic Imaging and 3 Tesla MR Fingerprinting for Tumor Localization in Glioma Patients.Cancers · 2024Article
- Correlation between synthetic MRI relaxometry and apparent diffusion coefficient in breast cancer subtypes with different neoadjuvant therapy response.Insights into imaging · 2023Article
- Multiparametric MRI model with synthetic MRI, DWI multi-quantitative parameters, and differential sub-sampling with cartesian ordering enables BI-RADS 4 lesions diagnosis with high accuracy.Frontiers in oncology · 2023Article
- Contrast-free MRI quantitative parameters for early prediction of pathological response to neoadjuvant chemotherapy in breast cancer.European radiology · 2022Article
- T2 relaxation time for the early prediction of treatment response to chemoradiation in locally advanced rectal cancer.Insights into imaging · 2022Article
- [Differential diagnosis of benign and malignant breast lesions using quantitative synthetic magnetic resonance imaging].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022Article
- Feasibility study of 2D Dixon-Magnetic Resonance Fingerprinting (MRF) of breast cancer.European journal of radiology open · 2022Article
- Determining the longitudinal accuracy and reproducibility of TJournal of applied clinical medical physics · 2021Article
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- Preoperative volumetric synthetic magnetic resonance imaging of the primary tumor for a more accurate prediction of lymph node metastasis in rectal cancer.Quantitative imaging in medicine and surgery · 2021Article
- Multiparameter MRI Model With DCE-MRI, DWI, and Synthetic MRI Improves the Diagnostic Performance of BI-RADS 4 Lesions.Frontiers in oncology · 2021Article
- Multiexponential T2 relaxometry of benign and malignant adipocytic tumours.European radiology experimental · 2020Article
- A Diagnostic Algorithm using Multi-parametric MRI to Differentiate Benign from Malignant Myometrial Tumors: Machine-Learning Method.Scientific reports · 2020Article
- Repeatability and reproducibility of 3D MR fingerprinting relaxometry measurements in normal breast tissue.Journal of magnetic resonance imaging : JMRI · 2019Article
- Investigating the diagnostic value of quantitative parameters based on T2-weighted and contrast-enhanced MRI with psoas muscle and outer myometrium as internal references for differentiating uterine sarcomas from leiomyomas at 3T MRI.Cancer imaging : the official publication of the International Cancer Imaging Society · 2019Article
- Variation of TJournal of magnetic resonance imaging : JMRI · 2019Article
- Article
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Abstract
backgroundNeoadjuvant chemotherapy (NAC) is generally an effective method of reducing locally advanced malignant breast lesions before surgery; assessing the tumor response to NAC is crucial for patient management. T2 relaxation times can reflect biological state of lesions, may prove useful to assess the response to NAC.
objectivesTo investigate the lesion T2 relaxation times change in breast cancer neoadjuvant chemotherapy (NAC). PATIENTS AND
methodsIn total, 26 patients underwent NAC. Magnetic resonance imaging (MRI) T2 mapping was performed before and after NAC. The T2 relaxation times were obtained by using Functool software on an AW 43 workstation. The treatment response was assessed according to the pathological response classification. We aimed to analyze the changes in the T2 relaxation times before and after NAC as well as to study the relationship between the response and the lesion T2 relaxation times after NAC.
resultsIn 26 cases with NAC, the mean lesion T2 relaxation time before NAC was 81.34 ± 13.68 ms, compared with 64.50 ± 8.71 ms after NAC. Significant differences in the lesion T2 relaxation times existed between the pre- and post-NAC (P < 0.001) ; based on the pathology results, the mean lesion T2 relaxation times in 23 of the 26 responders (63.18 ± 8.37 ms) was shorter than in 3 of the 26 nonresponders (74.62 ± 2.32 ms) after NAC (P = 0.029).
conclusionIn breast cancer after NAC, the lesion T2 relaxation time was reduced in the responders, and this finding is potentially useful to assess the response to NAC.
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