Evidence map›Paper›PMID 27853374›Full record

ReviewTherapeutics and clinical risk management2016

Management of extrapulmonary sarcoidosis: challenges and solutions.

Khalid Al-Kofahi, Peter Korsten, Christian Ascoli, Shanti Virupannavar, Mehdi Mirsaeidi, Ian Chang, Naim Qaqish, Lesley A Saketkoo, Robert P Baughman, Nadera J Sweiss

Open access · goldAbstract readReview
In one paragraph

Review in Therapeutics and clinical risk management, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Gingival hyperplasia and conjunctival inflammatory nodule: a diagnostic pathway to sarcoidosis?Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024
    Article
  5. Article
  6. Article
  7. A single-center rheumatology experience of sarcoidosis: observations from 70 patients.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2023
    Article
  8. Article
  9. Common Clinical and Molecular Pathways between Migraine and Sarcoidosis.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Observational
  16. Review
  17. Article
  18. Article
  19. Article
  20. Extrapulmonary sarcoidosis in an atypical patient demographic.Proceedings (Baylor University. Medical Center) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

Khalid Al-KofahiDepartment of Molecular Biosciences, University of Kansas, Lawrence, KS, USA.
Peter KorstenDepartment of Nephrology and Rheumatology, University Medical Center Göttingen, Göttingen, Germany.
Christian AscoliDivision of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois at Chicago, Chicago, IL.
Shanti VirupannavarDivision of Rheumatology, University of Illinois at Chicago, Chicago, IL.
Mehdi MirsaeidiDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Miami Miller School of Medicine, Miami, FL.
Ian ChangDepartment of Medicine, Michigan State University College of Osteopathic Medicine, East Lansing, MI.
Naim QaqishDepartment of Gastroenterology, Hepatology and Nutrition, University of Buffalo, Buffalo, NY.
Lesley A SaketkooNew Orleans Scleroderma and Sarcoidosis Patient Care and Research Center, Louisiana State University Health Sciences Center, New Orleans, LA.
Robert P BaughmanDepartment of Medicine, University Medical Center of Cincinnati, Cincinnati, OH, USA.
Nadera J SweissDivision of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois at Chicago, Chicago, IL; Division of Rheumatology, University of Illinois at Chicago, Chicago, IL.
University of Illinois Chicago · USLouisiana State University Health Sciences Center New Orleans · USMichigan State University · USUniversitätsmedizin Göttingen · DEUniversity at Buffalo, State University of New York · USUniversity Medical Center · USUniversity of Kansas · USUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcoidosis is a chronic multisystem disease of unknown etiology characterized by noncaseating granulomas that most often involves the lungs, but frequently has extrapulmonary manifestations, which might be difficult to treat in individual patients.

objectiveTo review different disease manifestations, focusing on extrapulmonary organ systems, and to provide treatment options for refractory cases. MATERIALS AND

methodsWe performed a literature search using Medline and Google Scholar for individual or combined keywords of "sarcoidosis, extrapulmonary, treatment, kidney, neurosarcoidosis, cardiovascular, gastrointestinal, transplantation, musculoskeletal, rheumatology, arthritis, and skin". Peer-reviewed articles, including review articles, clinical trials, observational trials, and case reports that were published in English were included. References from retrieved articles were also manually searched for relevant articles. RESULTS AND

conclusionIsolated involvement of a single organ or organ system is rare in sarcoidosis, and thus all patients must be thoroughly evaluated for additional disease manifestations. Cardiac sarcoidosis and neurosarcoidosis may be life-threatening. Clinicians need to assess patients comprehensively using clinical, laboratory, imaging, and histopathological data to recommend competently the best and least toxic treatment option for the individual patient.

Indexed as

chronic granulomatous diseasesdiagnostic testsimmunosuppressive agentssarcoidosis

Identifiers

PMID27853374
PMCPMC5106225
OpenAlexW2553699976

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.