Evidence map›Paper›PMID 27853365›Full record

ArticleInternational journal of nanomedicine

Gene-silencing effects of anti-survivin siRNA delivered by RGDV-functionalized nanodiamond carrier in the breast carcinoma cell line MCF-7.

Yanzhao Bi, Yifan Zhang, Chunying Cui, Lulu Ren, Xueyun Jiang

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
  5. Review
  6. Article
  7. Application of Carbon Nanoparticles in Oncology and Regenerative Medicine.International journal of molecular sciences · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Multifunctional nanodiamonds in regenerative medicine: Recent advances and future directions.Journal of controlled release : official journal of the Controlled Release Society · 2017
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yanzhao BiSchool of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Beijing, People's Republic of China.
Yifan ZhangSchool of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Beijing, People's Republic of China.
Chunying CuiSchool of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Beijing, People's Republic of China.
Lulu RenSchool of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Beijing, People's Republic of China.
Xueyun JiangSchool of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Beijing, People's Republic of China.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanodiamond (ND) is a renowned material in nonviral small interfering RNA (siRNA) carrier field due to its unique physical, chemical, and biological properties. In our previous work, it was proven that ND could deliver siRNA into cells efficiently and downregulate the expression of desired protein. However, synthesizing a high-efficient tumor-targeting carrier using ND is still a challenge. In this study, a novel carrier, NDCONH(CH

Indexed as

Gene SilencingAnimalsApoptosisCell ProliferationDown-RegulationDrug CarriersHumansInhibitor of Apoptosis ProteinsMaleMCF-7 CellsMiceNanodiamondsNanomedicineOligopeptidesRNA, Small InterferingSurvivinarginyl-glycyl-aspartic acidBIRC5 protein, humanDrug CarriersInhibitor of Apoptosis ProteinsNanodiamondsOligopeptidesRNA, Small InterferingSurvivinNDCONH(CH2)2NH-VDGRRNAisiRNA carriersurvivin

Identifiers

PMID27853365
PMCPMC5104303
OpenAlexW2548649213

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.