Evidence map›Paper›PMID 27853322›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2017

Risk factors for group B streptococcal disease in neonates of mothers with negative antenatal testing.

V Parente, R H Clark, L Ku, C Fennell, M Johnson, E Morris, A Romaine, U Utin, D K Benjamin, J A Messina and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Risk of Early-Onset Neonatal Group B Streptococcal Disease With Maternal Colonization Worldwide: Systematic Review and Meta-analyses.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Neonatal Group BSaudi medical journal · 2024
    Article
  7. Article
  8. Vaginal Carriage of Group BMicrobiology insights · 2023
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

V ParenteDepartment of Pediatrics, Duke University, Durham, NC, USA.
R H ClarkPediatrix-Obstetrix Center for Research and Education, Sunrise, FL, USA.
L KuDepartment of Pediatrics, Duke University, Durham, NC, USA.
C FennellDuke Clinical Research Institute, Durham, NC, USA.
M JohnsonDuke Clinical Research Institute, Durham, NC, USA.
E MorrisDuke Clinical Research Institute, Durham, NC, USA.
A RomaineDuke Clinical Research Institute, Durham, NC, USA.
U UtinDuke Clinical Research Institute, Durham, NC, USA.
D K BenjaminDepartment of Pediatrics, Duke University, Durham, NC, USA.
J A MessinaDuke Clinical Research Institute, Durham, NC, USA.
P B SmithDepartment of Pediatrics, Duke University, Durham, NC, USA.
R G GreenbergDepartment of Pediatrics, Duke University, Durham, NC, USA.
Clinical Research Institute · USDuke University · US

Funding

Duke CTSA (Composite)UL1TR001117 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, LI, JENNIFER S · 2013 to 2017
$41.3M
Center for Molecular &Cellular Studies of Ped DiseaseK12HD043494 · NICHD · DUKE UNIVERSITY · PI REED, ANN M. · 2003 to 2017
$5.2M
Duke Research Training Program for PediatriciansT32HD043029 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2002 to 2017
$3.7M
Prevention of Invasive Candidiasis: PK, Safety, and Neurodevelopmental OutcomesR01HD057956 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2008 to 2012
$2.8M
Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTGT32AI100851 · NIAID · DUKE UNIVERSITY · PI ALEXANDER, BARBARA D · 2013 to 2022
$1.8M
Mentorship of early-career pediatricians in quantitiative methods and therapeuticK24HD058735 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2009 to 2018
$1.5M
Multidisciplinary Neonatal Training GrantT32HD043728 · NICHD · DUKE UNIVERSITY · PI GOLDBERG, RONALD · 2005 to 2014
$1.3M
NIH Summer Research Experience Programs (R25)R25HD076475 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2013 to 2023
$1.1M
PATIENT SAFETY RESEARCH DURING NEONATAL CARE (R21)R21HD080606 · NICHD · DUKE UNIVERSITY · PI SMITH, PHILLIP BRIAN · 2015 to 2016
$457k
NCATS NIH HHS UL1 TR001117NIAID NIH HHS HHSN272201500006CNIAID NIH HHS T32 AI100851NICHD NIH HHS HHSN275201000003CNICHD NIH HHS HHSN275201000003INICHD NIH HHS K12 HD043494NICHD NIH HHS K24 HD058735NICHD NIH HHS R01 HD057956NICHD NIH HHS R21 HD080606NICHD NIH HHS R25 HD076475NICHD NIH HHS T32 HD043029NICHD NIH HHS T32 HD043728
6 · The paper itself

Abstract

objectiveThe aim of this study was to identify risk factors for early-onset group B Streptococcus (EOGBS) disease in neonates of mothers with negative antenatal screening. STUDY

designWe performed a retrospective cohort study of neonates born to mothers with negative antenatal GBS screening between 2002 and 2012. Our primary outcome was EOGBS infection. We used multivariable logistic regression to assess factors associated with EOGBS.

resultsEOGBS was confirmed in 492 of the 179 818 neonates that met the study inclusion criteria. Risk factors for EOGBS included black race (reference: white, odds ratio (OR) =1.81 (95% confidence interval: 1.43, 2.31)), maternal age <18 years (reference: >35 years, OR=2.63 (1.54, 4.51)) and maternal age 18 to 35 years (reference: >35 years, OR=1.94 (1.30, 2.88)).

conclusionMaternal age <18 years and black race were the strongest predictors of EOGBS. Further research investigating contributors to the discordance between screening results and neonatal outcomes in these populations is needed.

Indexed as

Black PeopleMaternal AgeAdolescentAdultAntibiotic ProphylaxisBlack or African AmericanDatabases, FactualFemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalLogistic ModelsMaleMultivariate AnalysisNorth CarolinaOdds Ratio

Identifiers

PMID27853322
PMCPMC5280520
OpenAlexW2552810358

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.