ArticleScientific reports2016
A comparison of biological characteristics of three strains of Chinese sacbrood virus in Apis cerana.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 37 citations in OpenAlex.
- Larval Metabolic and Physiological Mechanisms Underlying Resistance to Chinese Sacbrood Virus inInsects · 2025Article
- Discovery of SNP Molecular Markers and Candidate Genes Associated with Sacbrood Virus Resistance inInternational journal of molecular sciences · 2023Article
- Comparison of the gut microbiome of sacbrood virus-resistant and -susceptible Apis cerana from South Korea.Scientific reports · 2022Article
- Differential Viral Distribution Patterns in Reproductive Tissues ofFrontiers in veterinary science · 2021Article
- Genomic Sequencing and Comparison of Sacbrood Viruses fromPathogens (Basel, Switzerland) · 2020Article
- Visualizing Sacbrood Virus of Honey Bees via Transformation and Coupling with Enhanced Green Fluorescent Protein.Viruses · 2020Article
- Identification of Immune Response to Sacbrood Virus Infection inFrontiers in genetics · 2020Article
- Prevalence of bee viruses in Apis cerana cerana populations from different locations in the Fujian Province of China.MicrobiologyOpen · 2019Article
- Article
- Identification of the Novel Host Protein Interacting With the Structural Protein VP1 of Chinese Sacbrood Virus by Yeast Two-Hybrid Screening.Frontiers in microbiology · 2019Article
- Article
- Purification of Chinese Sacbrood Virus (CSBV), Gene Cloning and Prokaryotic Expression of its Structural Protein VP1.Molecular biotechnology · 2018Article
- Preparation and Application of Egg Yolk Antibodies Against Chinese Sacbrood Virus Infection.Frontiers in microbiology · 2018Article
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7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We selected and sequenced the entire genomes of three strains of Chinese sacbrood virus (CSBV): LNQY-2008 (isolated in Qingyuan, Liaoning Province), SXYL-2015 (isolated in Yulin, Shanxi Province), and JLCBS-2014 (isolated in Changbaishan, Jilin Province), by VP1 amino acid (aa) analysis. These strains are endemic in China and infect Apis cerana. Nucleotide sequences, deduced amino acid sequences, genetic backgrounds, and other molecular biological characteristics were analysed. We also examined sensitivity of these virus strains to temperature, pH, and organic solvents, as well as to other physicochemical properties. On the basis of these observations, we compared pathogenicity and tested cross-immunogenicity and protective immunity, using antisera raised against each of the three strains. Our results showed that compared with SXYL-2015, LNQY-2008 has a 10-aa deletion and 3-aa deletion (positions 282-291 and 299-301, respectively), whereas JLCBS-2014 has a 17-aa deletion (positions 284-300). However, the three strains showed no obvious differences in physicochemical properties or pathogenicity. Moreover, there was immune cross-reactivity among the antisera raised against the different strains, implying good protective effects of such antisera. The present study should significantly advance the understanding of the pathogenesis of Chinese sacbrood disease, and offers insights into comprehensive prevention and treatment of, as well as possible protection from, the disease by means of an antiserum.
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