Trial reportScientific reports2016
Resting-state high-frequency heart rate variability is related to respiratory frequency in individuals with severe mental illness but not healthy controls.
Trial report in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Publication guidelines for human heart rate and heart rate variability studies in psychophysiology-Part 1: Physiological underpinnings and foundations of measurement.Psychophysiology · 2024Guideline
- Benefits from one session of deep and slow breathing on vagal tone and anxiety in young and older adults.Scientific reports · 2021Trial
- Toward an Embodied Medicine: A Portable Device with Programmable Interoceptive Stimulation for Heart Rate Variability Enhancement.Sensors (Basel, Switzerland) · 2018Trial
- Diurnal Variation and Twenty-Four Hour Sleep Deprivation Do Not Alter Supine Heart Rate Variability in Healthy Male Young Adults.PloS one · 2017Trial
- Heart rate variability in patients with atrial fibrillation of sinus rhythm or atrial fibrillation: chaos or merit?Annals of medicine · 2025Review
- A focus on the assessment of the autonomic function using heart rate variability.Global cardiology science & practice · 2025Review
- Influence of Respiratory Frequency of Slow-Paced Breathing on Vagally-Mediated Heart Rate Variability.Applied psychophysiology and biofeedback · 2024Article
- Review
- Capturing inter-individual variability in stress dynamics with heart rate traces reveals activity in the bilateral hippocampus, amygdala, and insula.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Clinical Implication of Maumgyeol Basic Service-the 2 Channel Electroencephalography and a Photoplethysmogram-based Mental Health Evaluation Software.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023Article
- Association of Autonomic Activation with traumatic reminder challenges in posttraumatic stress disorder: A co-twin control study.Psychophysiology · 2023Article
- Investigating the Relationship between Electroconvulsive Therapy and Heart Rate Variability: A Systematic Review.Advanced biomedical research · 2023Review
- Distress disorder histories predict HRV trajectories during and after stress.Psychoneuroendocrinology · 2022Article
- Respiration Based Non-Invasive Approach for Emotion Recognition Using Impulse Radio Ultra Wide Band Radar and Machine Learning.Sensors (Basel, Switzerland) · 2021Article
- Cardiovascular reactivity as a measure of irritability in a transdiagnostic sample of youth: Preliminary associations.International journal of methods in psychiatric research · 2021Article
- Recognizing emotions in bodies: Vagus nerve stimulation enhances recognition of anger while impairing sadness.Cognitive, affective & behavioral neuroscience · 2021Article
- Non-Invasive Driver Drowsiness Detection System.Sensors (Basel, Switzerland) · 2021Article
- How to Use Heart Rate Variability: Quantification of Vagal Activity in Toddlers and Adults in Long-Term ECG.Sensors (Basel, Switzerland) · 2020Article
- The control mechanisms of heart rate dynamics in a new heart rate nonlinear time series model.Scientific reports · 2020Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heart rate variability (HRV) has become central to biobehavioral models of self-regulation and interpersonal interaction. While research on healthy populations suggests changes in respiratory frequency do not affect short-term HRV, thus negating the need to include respiratory frequency as a HRV covariate, the nature of the relationship between these two variables in psychiatric illness is poorly understood. Therefore, the aim of this study was to investigate the association between HRV and respiratory frequency in a sample of individuals with severe psychiatric illness (n = 55) and a healthy control comparison group (n = 149). While there was no significant correlation between HF-HRV and respiration in the control group, we observed a significant negative correlation in the psychiatric illness group, with a 94.1% probability that these two relationships are different. Thus, we provide preliminary evidence suggesting that HF-HRV is related to respiratory frequency in severe mental illness, but not in healthy controls, suggesting that HRV research in this population may need to account for respiratory frequency. Future work is required to better understand the complex relationship between respiration and HRV in other clinical samples with psychiatric diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.