Evidence map›Paper›PMID 27853201›Full record

ReviewNature2016

The effects of Δ

Michael A P Bloomfield, Abhishekh H Ashok, Nora D Volkow, Oliver D Howes

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Nature, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06435650 (The Use of Mindful Compassion and Cannabis Suppositories for Anal Pain Among Men Who Have Sex With Men), which is not on this map. Cited by 176 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
176citing papers in PubMed, 9 pooled it
23.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06435650 nacompletednot on this mapstarted 2023, after this paper: background citation

The Use of Mindful Compassion and Cannabis Suppositories for Anal Pain Among Men Who Have Sex With Men

TypeinterventionalSponsorLondon Metropolitan UniversityRan2023 to 2024Enrolled52ConditionsPain, Sexual Intercourse, MArmsCannabis suppositories and mindful-compassion for anal pain, Mindful-compassion
3 · Its place in the literature

Who cites it

176 citing papers in PubMed, 9 syntheses or guidelines pooled it, 359 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Evidence for pro-cognitive benefits of cannabinoids in people with bipolar disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Trial
  11. ΔBiological psychiatry. Cognitive neuroscience and neuroimaging · 2026
    Trial
  12. Trial
  13. Trial
  14. Intoxication due to Δ9-tetrahydrocannabinol is characterized by disrupted prefrontal cortex activity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Trial
  15. Identification of ∆9-tetrahydrocannabinol (THC) impairment using functional brain imaging.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Trial
  16. Trial
  17. Trial
  18. Trial
  19. Article
  20. The role of subcortical brain tissue iron as an indicator of dopamine neurophysiology in adolescent cannabis use.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article

116 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Michael A P BloomfieldPsychiatric Imaging Group, Robert Steiner MR Unit, MRC Clinical Sciences Centre, Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.
Abhishekh H AshokPsychiatric Imaging Group, Robert Steiner MR Unit, MRC Clinical Sciences Centre, Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.
Nora D VolkowNational Institute on Drug Abuse, National Institutes of Health, 6001 Executive Boulevard, Bethesda, Maryland 20892-9561, USA.
Oliver D HowesPsychiatric Imaging Group, Robert Steiner MR Unit, MRC Clinical Sciences Centre, Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.
Imperial College London · GBNational Institutes of Health · USUniversity College London · GB

Funding

Neurobiology of Substance Abuse and AddictionZIAAA000550 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI VOLKOW, NORA D. · 2009 to 2025
$115.1M
Medical Research Council G0700995Medical Research Council MC_U120097115Medical Research Council MR/N026063/1
6 · The paper itself

Abstract

The effects of Δ

Indexed as

AnimalsBehavior, AnimalBrainCell ShapeDopamineDopaminergic NeuronsDronabinolEatingHumansPost-Synaptic DensityPresynaptic TerminalsReceptor, Cannabinoid, CB1DopamineDronabinolReceptor, Cannabinoid, CB1

Identifiers

PMID27853201
PMCPMC5123717
OpenAlexW2554987321

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.